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Douglas Labs

Uni-Joint Formula
by Douglas Labs
120 Capsules

Support For Structure And Function Of Healthy Joints*

Our Price: $61.20

Uni-Joint Formula, provided by Douglas Laboratories, is a synergistic and comprehensive combination of natural ingredients, including glucosamine sulfate, bovine and shark cartilage/mucopolysaccharides, and bromelain, carefully formulated and specifically designed to ease discomfort while maintaining and restoring the structure and function of healthy joints.*

FUNCTIONS
Glucosamine is a naturally occurring amino sugar found in glycosoaminoglycans (mucopolysaccharides), integral components of the proteoglycans found in joint cartilage. Proteoglycans are large carbohydrate rich structures that provide resiliency, load distribution, shock- absorption, compression and lubricating properties to joints and connective tissues. Dietary glucosamine serves as an immediate precursor for glycosaminoglycan synthesis, and also stimulates incorporation of other precursors into the connective tissue matrix.*

The availability of glucosamine is an integral part of the synthesis of glycosaminoglycans and proteoglycans that are necessary during the constant remodeling that aging cartilage undergoes. Thus, the maintenance of healthy aging cartilage may be improved with enhanced deposition of glycosaminoglycans and proteoglycans.*

Bioavailability of oral glucosamine sulfate is excellent. It is absorbed intact, and utilized very quickly by all tissues, including connective tissues. Glucosamine sulfate is more efficiently used for connective tissue metabolism than other glucosamine sources, such as cartilage extracts or chondroitin sulfate. Glucosamine sulfate is a well recognized, highly effective source of glucosamine for glycosaminoglycan and proteoglycan synthesis in all connective tissues, such as cartilage, ligaments, tendons, skin, and bone.*

Bromelain, a protease from the pineapple plant, reduces the production of proinflammatory prostaglandins by modulating the arachidonate cascade. It has the ability to help modulate normal inflammatory processes and support the discomfort associated with aging joints.*

NOTE: Special Order Product Product - Special Shipping Required
This is a Special Order Product. We stock this in low quantities, due to low-to-moderate sales volume. If the product is on hand, we will ship immediately. If we are out of stock at the time of your order, we will order directly from the manufacturer, on your behalf. This could add an additional 2 to 5 business days to your delivery time.

Supplement Facts Serving Size: One (1) Capsule Servings Per Container: 120

	Amount Per Serving	Daily Value
Glucosamine Sulfate	250 mg	**
Sea Cucumber Powder (Pseudocalochirus Axiologus)	150 mg	**
Shark Cartilage Powder	150 mg	**
Bromelain (Lower Stem, Pineapple Plant)	150 mcu	**
A Proprietary Blend	50 mg	**
Bovine Cartilage
Mucopolysaccharides
Yucca Leaf Powder	5 mg	**
Bilberry Fruit Extract	5 mg	**

** Daily Value Not Established. Percent Daily Values are based on a 2,000 calorie diet.

Other Ingredients

Cellulose, Gelatin Capsule, Silica, Stearates (Vegetable Source)

Suggested Use

As a dietary supplement, one (1) capsule daily, or more as directed by physician.

Warnings

Keep out of reach of children. ... Store in a cool, dry place, away from direct light. ... Do not use if outer seal is missing.

Allergen Info

This product contains NO yeast, wheat gluten, soy protein, milk/dairy, corn, sodium, sugar, starch, artificial coloring/flavoring, or preservatives.

Applicable Functions

Joint Comfort, Joint Health, Torn Connective Tissue, Torn Ligaments

Related Structure Groups

Bones, Cartilage, Connective Tissue, Joints, Ligament, Skin, Tendon

REFERENCES

Giordano N, Nardi P, Senesi M, Palumbo F, Battisti E, Gonnelli S, Franci B, Campagna MS, Gennari C. [The efficacy and safety of glucosamine sulfate in the treatment of gonarthritis]. Clin Ter 1996;147:99-105.

Gottlieb MS. Conservative management of spinal osteoarthritis with glucosamine sulfate and chiropractic treatment. J Manipulative Physiol
Ther 1997;20:400-14.

Kelly GS. The role of glucosamine sulfate and chondroitin sulfates in the treatment of degenerative joint disease. Altern Med Rev 1998;3:27-39.

Leeb BF, Petera P, Neumann K. [Results of a multicenter study of chondroitin sulfate (Condrosulf) use in arthroses of the finger, knee and
hip joints]. Wien Med Wochenschr 1996;146:609-14.

Leffler CT, Philippi AF, Leffler SG, Mosure JC, Kim PD. Glucosamine, chondroitin, and manganese ascorbate for degenerative joint disease of the knee or low back: a randomized, double-blind, placebo-controlled pilot study. Mil Med 1999;164:85-91.

Lopes Vaz A. Double-blind clinical evaluation of the relative efficacy of ibuprofen and glucosamine sulphate in the management of osteoarthrosis of the knee in out-patients. Curr Med Res Opin 1982;8:145-9.

Lotz-Winter H. On the pharmacology of bromelain: an update with special regard to animal studies on dose-dependent effects. Planta Med
1990;56:249-53.

McCarty MF. Enhanced synovial production of hyaluronic acid may explain rapid clinical response to high-dose glucosamine in osteoarthritis. Med Hypotheses 1998;50:507-10.

Qiu GX, Gao SN, Giacovelli G, Rovati L, Setnikar I. Efficacy and safety of glucosamine sulfate versus ibuprofen in patients with knee
osteoarthritis. Arzneimittelforschung 1998;48:469-74.

Setnikar I, Cereda R, Pacini MA, Revel L. Antireactive properties of glucosamine sulfate. Arzneimittelforschung 1991;41:157-61.

Shankland WE, 2nd. The effects of glucosamine and chondroitin sulfate on osteoarthritis of the TMJ: a preliminary report of 50 patients.
Cranio 1998;16:230-5.

Tapadinhas MJ, Rivera IC, Bignamini AA. Oral glucosamine sulfate in the management of arthrosis: report on a multi-centre open
investigation in Portugal. Pharmatherapeutica 1982;3:157-68.

Taussig SJ, Batkin S. Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application. An update. J
Ethnopharmacol 1988;22:191-203.

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Our Price: $61.20


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