SAMe by NOW Foods 30 Vegetarian Tablets Potentially Enhances Mood and Lifts Spirits* Our Price: $10.32 Retail Price: $16.99 You Save: $6.67 each, a 39% Savings!
SAMe is a supplement formed in the body by an enzymatic reaction between adenosine-triphosphate (ATP) and methionine. It was discovered in 1952 in Italy and has been researched and manufactured there. SAMe works closely with folic acid and vitamin B-12 and functions as a methyl donor. This nutrient carries and donates methyl molecules necessary to facilitate the manufacture of DNA and brain neurotransmitters.* Tissue levels of SAMe are typically low in the elderly.
Nervous System Support* With B-vitamin Cofactors Supports Emotional Well-Being* Supports Joint Health* Enteric Coated Vegetarian Formula
Please note: The manufacturer of this brand of SAMe does not require special refrigerated handling of this product. However, refrigeration of SAMe may increase its shelf life. Therefore, we refrigerate all of the SAMe stock in our warehouse until shipping, and advise you that refrigeration once you have received and opened the product may extend its shelf life. You may also consider choosing expedient shipping, especially during hot summer weather.
Additional Sizes Available
30 Vegetarian Tablets - 100 mg of SAMe (S-Adenosylmethionine)
30 Vegetarian Tablets - 200 mg of SAMe (S-Adenosylmethionine)
30 Vegetarian Tablets - 400 mg of SAMe (S-Adenosylmethionine)
60 Vegetarian Tablets - 100 mg of SAMe (S-Adenosylmethionine)
60 Vegetarian Tablets - 200 mg of SAMe (S-Adenosylmethionine)
60 Vegetarian Tablets - 400 mg of SAMe (S-Adenosylmethionine)
Supplement Facts
One (1) Vegetarian Tablet Contains:
Amount Per Serving
SAMe (S-Adenosylmethionine)(from 200 mg of S-Adenosyl-L-Methionine Disulfate Tosylate) 100 mg
Triethyl Citrate, Stearic Acid (Vegetable Source), Silica, Methacrylic Acid, Magnesium Stearate (vegetable source), Croscarmellose Sodium, Citric Acid, Cellulose, Ascorbic Acid, Contains no sugar, salt, starch, yeast, wheat, gluten, soy, milk, egg, shellfish or preservatives. Vegetarian/Vegan Product. As a dietary supplement, one (1) vegetarian tablet, two to four times (2-4x) daily, preferably on an empty stomach, or as directed by a healthcare practitioner. Refrigeration recommended after opening. Individuals with bipolar (manic) depression should not take SAMe unless under professional medical supervision. Amino Acid , Amino Acids Depleted ATP Production , Depressive Tendencies , Vitamin Deficiency Brain , Brain Chemistry , Lung Depressed , Fretful , Melancholy What is SAMe?
SAMe (S-adenosylmethionine or S-Adenosyl-L-Methionine) is a naturally occurring compound found in all human tissue and organs. It is a “building block” necessary for the production of many compounds produced by your body, and is used in over 35 different biochemical reactions. SAMe actually donates a part of itself to form these new compounds through a process called methylation, or transmethylation. SAMe is one of the few dietary supplements on the market today that combines the benefits of several nutrients into one, because the body uses the substances produced from SAMe for numerous body processes, including detoxification.
Are there any side effects associated with SAMe supplementation?
SAMe is a very safe dietary supplement. Minor side effects include nausea and gastrointestinal irritation, probably due to its sulfur content. But these were only noted at very high doses (1200-1600mg), and the symptoms diminished with continued use. Persons suffering from manic depression (bipolar disorder) should not take SAMe without prior consultation with their physician. If you experience any of these symptoms, it may not be the right supplement for you. The mineral Sulfur is not related to sulfa drugs or allergies related to sulfa drugs.
Why is the dosage information with SAMe supplements so confusing?
SAMe in its pure form as found in human cells has a very short life span and is rapidly metabolized into other necessary compounds as needed, which is good! However, this natural form does not allow for the production of a stable, effective dietary supplement. It took scientists years to come up with a way to stabilize SAMe so it could be manufactured as a dietary supplement. It was finally discovered that SAMe (S-Adenosyl-L-Methionine) must be manufactured in a stable “salt” form (for example, as S-Adenosyl-L-Methionine Disulfate Tosylate) to prevent rapid degradation. In this form, you will actually get 200mg of SAMe compounded in a stable form. However, only half of this 200mg is pure SAMe (S-Adenosyl-L-Methionine). Please note that this “salt” is not a significant source of sodium.
Are there size or color variations with your SAMe products, and should SAMe be refrigerated?
Because of the nature of SAMe, NOW takes special precautions when packaging this product. Extensive stability testing was performed in order to create this uniquely stabilized product. We bottle SAMe in amber glass bottles to keep light exposure to a minimum, and keep SAMe products refrigerated in our plant until shipping. It is not necessary to keep SAMe refrigerated after purchase, but it will extend the shelf life of the product. The bottle should be kept closed between uses, away from excessive heat and moisture.
Because SAMe is a natural product, there can be variations in color, usually ranging from white to pale yellow or tan. This is normal and does affect the quality of the product. You may also notice a difference in tablet size between different potencies. SAMe is available in 100mg, 200mg, and 400mg enteric-coated tablets, all coming in different sizes.
As the building blocks of protein, amino acids are vital to health. Next to water, amino acids in the form of proteins make up the greatest portion of our body weight. They comprise tendons, muscles and ligaments; organs and glands; hair and nails; important bodily fluids, and are a necessary part of every cell in the body.
There are over 20 amino acids, separated into two categories – essential and non-essential. Essential amino acids are those that cannot be manufactured by your body, hence, it is essential that you obtain them from your diet. Non-essential amino acids can be manufactured by your body, however, your body must have the right combination of essential amino acids and supporting nutrients to optimize healthy protein maintenance, so supplementation may be desirable.
Raw Materials
Superior supplements begin with superior raw materials. As the foundation that supports our line of quality products, NOW tests raw materials for contaminants, heavy metals, pesticides and fillers. Our philosophy remains unfaltering; we always start with the purest, freshest raw materials to ensure that the finished product is the best it can be. By partnering with some of the most trusted names in the industry including Lonza, PL Thomas, Cyanotech, Inter-Health, Hoffman LaRoche, Sabinsa and others, NOW is proud to provide unadulterated natural products that are safe, potent and true to their claim.
Natural Ingredients
Mad Cow Free
Growth Hormone Free
Exacting Heavy Metal and Pesticide Specifications
Pure, Fresh Raw Materials, Always
Good Manufacturing Practices
NOW's commitment to Good Manufacturing Practice (GMP) is evident in everything we do. As one of the first companies to receive GMP certification from the NNFA, in addition to being one of the very few to maintain a consistent 'A' rating, we've remained steadfast in our commitment to good manufacturing practices. Our clean, controlled and technologically advanced production facility is regularly inspected by the Food and Drug Administration, and has been certified organic by Quality Assurance International.
Longstanding NNFA GMP "A" Rating FDA Inspected Organic Certification by QAI Clean, Modern, Controlled Production Facility
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Our Price: $10.32 Retail Price: $16.99 You Save: $6.67 each, a 39% Savings!
