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SAMe - S-Adenosylmethionine
by Nutricology
20 Tablets
Natural Form Of Bioactive Methionine
Our Price: $11.99
Retail Price: $24.00
You Save: $12.01 each, a 50% Savings! | 
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S-Adenosylmethionine is utilized by almost every cell in the body. Supplementing the SAMe, therefore, has a wide range of potential benefit.* SAMe has been widely reported in medical literature to support mood balance, joint health, and proper liver function. SAMe has also been reported to lower elevated levels of homocysteine often associated with cardiovascular and musculoskeletal conditions.* This product is hypoallergenic.* SAMe is a natural form of bioactive methionine. It is a result of the conversion of methionine by ATP and the enzyme SAMe synthetase. It is used by the body to produce the neurotransmitters dopamine, norepinepherine, and serotonin. It is also used in the production and protection of DNA and RNA, and in the production of phosphatidylcholine, which may be beneficial in keeping cell membranes in a youthful state.* SAMe is used in the following metabolic pathways: methylation, synthesis of polyamines, and trans-sulphuration. Methylation is involved in protection or transformation of other molecules such as DNA and homocysteine. Synthesis of polyamines results in cell growth, gene expression, neuron regeneration, etc., and trans-sulphuration is the synthesis of L-cysteine, glutathione and other sulfate groups, which are involved in liver support and detoxification. In Chinese medicine the liver is thought of as the seat of emotion, and compromised liver function is thought to be involved in mood. Research has shown SAMe to support liver enzymes within normal levels.* It is suspected that SAMe protects synovial cells by reversing glutathione depletion, thereby being beneficial for compromised joint function and degeneration. Studies have shown that during joint degeneration the synovial fluid may contain damaging cytokines (TNF) and free radicals. In addition, SAMe may protect proteoglycans (protein cells composed of keratin and chondroitin sulfate) and chondrocytes (cartilage cells, that make proteoglycans and collagen), the components of the spongy tissues between joint called cartilage that breaks down during joint degeneration.* For optimal metabolism and utilization of SAMe, it should be taken with B6, B12 and folic acid. Please note that while the manufacturer of this brand of SAMe does not require special refrigerated handling of this product, refrigeration may increase its shelf life. Therefore, we refrigerate all of the SAMe stock in our warehouse until shipping, and advise that refrigeration once you have received and opened the product may extend its shelf life. You may also consider choosing expedient shipping, especially during hot summer weather.*
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Supplement FactsServing Size: Two (2) Tablets
Servings Per Container: 10 | | | | Amount
Per Serving | Daily
Value | | SAMe (S-Adenosylmethionine) | 400 mg | ** | |
** Daily Value Not Established. Percent Daily Values are based on a 2,000 calorie diet. |
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| Cellulose, Citric Acid, Croscarmellose Sodium, Glyceryl Triacetate, Hydroxypropyl Methylcellulose Phthalate, Mannitol, Silica, Sodium Starch Glycolate, Stearic Acid, Titanium Dioxide, Yellow Ochre |
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| As a dietary supplement, one (1) or two (2) tablets one to four (1-4) times daily between meals, or more as directed by a healthcare practitioner. |
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| If pregnant, nursing, or taking prescription medication, consult your healthcare practitioner prior to use. ... Keep in a cool, dry place, tightly capped. ... Keep out of reach of children. |
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| This product is of the highest quality and purity obtainable, free of all common allergens (antigens), and does not contain preservatives, diluents, or artificial additives. |
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| Bioenergetic, DNA Nutrition, Emotional remedies, Mood Support |
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| Cell Formation, Cholesterol Health, Damaged Tissue, Depressive Tendencies, Hansen's, Joint Health, Seasonal Affective Disorder, Thromboangiitis Obliterans |
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| Amino Acids, Brain Chemistry, DNA / RNA, Hypothalamus |
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| Blah, Brain Fog, Depressed, Depression, Sadness |
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 NutriCology, Inc., established in 1979, is an innovative leader in the research and formulation of nutritional supplements and is one of the very first allergy-oriented hypoallergenic nutritional supplement companies. The company is recognized worldwide for the quality, purity and efficacy of its targeted nutritional supplement line, consisting of more than 200 products. Over 4,000 physicians and healthcare practitioners worldwide currently purchase NutriCology's products and recommend these supplements to their patients.Stephen Levine, Ph.D., founder of NutriCology, Inc., graduated Cum Laude from the State University College in Buffalo, NY and obtained his Ph.D. from the University of California, Berkeley. Dr. Levine was a Horace and Edith King Davis Memorial Fellow, the recipient of an NIH Training Grant, and a Predoctoral Fellow (1972-1976). Dr. Levine is internationally recognized as one of the foremost innovative leaders and researchers in nutritional supplement formulation. He lectures internationally and holds editorial positions in several professionally sought after publications. Dr. Levine is also known worldwide as an author of the book "Antioxidant Adaptation: Its Role in Free Radical Pathology," which he co-authored with Dr. Parris Kidd in 1985. Their book is considered a leading resource on this subject. Dr. Levine also leads NutriCology's research and development. He is recognized internationally for his mission of creating state-of-the-art supplements especially designed for allergic individuals. For almost 30 years, Dr. Levine has dedicated himself to the latest research and the passionate pursuit of cutting-edge nutritional supplements. Dr. Levine was one of the first to introduce truly hypoallergenic products to the market, and developed the very first Buffered Vitamin C product. Dr. Levine's antioxidant research is legendaryin that it created a unique, broad spectrum integration of the available data with a very expanded perspective, which remains one of the most sophisticated antioxidant presentations even today. Over the past three decades, Dr. Levine has collaborated with the medical community. When asked about his work thus far, he states, "It has been my greatest pleasure working with progressive physicians to develop nutraceutical products which reduce suffering and improve the health of their patients." |
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According to Taber’s Medical Dictionary, “hypoallergenic” is defined as: “Diminished potential for causing an allergic reaction”. We define hypoallergenic as “free of all common allergens,” specifically: wheat, corn, soy, gluten, yeast, dairy, and eggs. Many very sensitive individuals who react to supplements in general are able to tolerate NutriCology products.
Since our inception in 1979 we have been using only the purest, and whenever possible, the lowest allergy potential natural ingredients. While many of the nutrients in our formulas are synthesized from natural substances (plant sources), which as a whole may contain antigens, the synthesizing process removes the molecules of the desired nutrient from the original substance, and in the processing, a great percentage of the antigens and allergens are left behind. The final material then has extremely low allergy potential.
This is not to say that no one will react to any of our hypoallergenic formulas, as some extremely sensitive people may. However, the potential for an allergic reaction is low, and the feedback from many of our extremely allergic and sensitive customers is that NutriCology supplements are often the only products they are able to tolerate.
New Allergen Labeling Regulations
As a result of the Food Allergen Labeling and Consumer Protection Act of 2004, effective January 1, 2006, the FDA requires manufacturers to identify the presence of eight major food allergens on all product labels.
The term “major food allergen” means any of the following:
• milk
• egg
• fish
• crustacean shellfish
• tree nuts
• peanuts
• wheat
• soybeans
• any ingredient derived from the above listed foods
It is important to understand that while an ingredient may have been derived from a common allergen, we are required by law to list that allergen on the label as a source of the ingredient, even if it does not contain any of the actual substance. For example, 100%-pure glucosamine sulfate does not contain any actual shellfish, but we are required to indicate the source material (shrimp, crab, lobster) on the label. Full Disclosure Labeling
Nutricology fully discloses all ingredients, both active and inactive on every product label, so you can make fully informed choices. Vegetarian Capsules
Nutricology is currently in the process of converting most of our existing products to vegetarian capsules, and all new products are being made with vegetarian capsules. |
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NutriCology fully discloses all ingredients, both active and inactive, on every product label, so you can make fully informed choices for your patients.
Furthermore, the following is a list of inactive ingredients used in some of our products. These may be called fillers and/or excipients as defined by the Food Chemical Codex. These are nutrient compounds which are utilized for their physical properties to aid in the supplement production process. They are derived from edible sources and are generally free of common allergens. To determine which natural additives are included in a specific product, please refer to the supplement facts panel.Cellulose Powder is derived from fibrous plant material, is insoluble in water and is used as a filler. In addition to being used as a filler, cellulose powder is sold as an individual supplement as a pure insoluble fiber, and is extremely well tolerated. Silicon Dioxide, or silica, is one of the most common chemical compounds. Silica plays an important role in biological processes. Most rocks and minerals are made of silicon dioxide and other minerals. Silica is insoluble in water and is used for its drying properties. Stearic Acid is an 18 carbon, naturally occurring saturated fatty acid. It is a component of membrane structure and is utilized for its lubricating properties. Magnesium Stearate contains stearic acid and magnesium palmitate, which is magnesium salt of a 16 carbon saturated fatty acid, also common in membrane structure. It is also utilized for its lubricating properties. Dicalcium phosphate (calcium phosphate, dibasic) is a white, odorless, tasteless powder that is stable in air. It is practically insoluble in water, but is readily soluble in hydrochloric acid. L-leucine is an essential branched-chain amino acid, found in almost all animal and vegetable proteins. As an excipient in our formulas, pharmaceutical grade L-leucine is presented in minute amounts and is used as a lubricant. |
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Since 1979, NutriCology has used only the purest raw materials available, and has implemented strict quality control procedures in every stage of production, including inspection of raw materials, manufacturing, packaging, and storing. For many years we have used the same manufacturers to produce our capsules and tablets to ensure consistency. In our facility in Alameda, California we bottle, label, and ship our finished products. NutriCology is currently licensed by the California Department of Health Services, Food and Drug Branch. Our registration number is 0021150. Independent Third Party Laboratories
In addition to our in-house quality control department, we use independent analytical laboratories to test raw materials as well as our finished products. They are assayed for identity, purity and potency. Our products are confirmed to contain no less than 100% of the contents listed on every label. Microbial and heavy metals analyses are also conducted on all applicable products. GMP Standards
Our products are manufactured under the recognized principles of current Good Manufacturing Practice (cGMP) proposed by the FDA. The GMP standards are applied to a wide variety of procedures associated with the manufacturing of dietary supplements, including approval of raw materials, production and process controls, laboratory testing, and product packaging, labeling and distribution. Procedures of Analysis
We utilize a number of advanced methods of analysis, including high performance liquid chromatography (HPLC), IR and UV-VIS spectroscopy, capillary electrophoresis (CE), inductively coupled plasma-mass spectrometry (ICP-MS), and atomic absorption (AA), along with biochemistry and wet chemistry techniques. |
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Our Price: $11.99
Retail Price: $24.00
You Save: $12.01 each, a 50% Savings! |
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