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Douglas Labs

Pan-Ox-5
by Douglas Labs
90 Tablets

Supports Digestive Health*

Our Price: $18.10

Pan-Ox-5, provided by Douglas Laboratories, is a synergistic dietary enzyme blend that is specially formulated for digestive support.*

FUNCTIONS
The pancreas supplies the major digestive enzymes that catalyze the breakdown of starches (carbohydrates), proteins, and fats so that the breakdown products can be absorbed in the upper small intestine.*

Some carbohydrate digestion takes place in the mouth by salivary amylase, but pancreatic amylase is the major carbohydrate-digesting enzyme. Amylases break down starches to maltose and maltotriose, which are further hydrolyzed into glucose by the disaccharidases of the mucosal cells, and then absorbed. Although cellulose is indigestible by pancreatic and intestinal enzymes, the microflora within the large intestine may degrade it and produce uncomfortable symptoms in the process.*

Despite the fact that fat digestion starts in the mouth with the action of salivary lipase, the great majority of fat triglycerides are digested by pancreatic lipase secreted by the exocrine pancreas into the duodenum. Lipases break down triglycerides into monoglycerides and free fatty acids, which are efficiently absorbed in the upper small intestine.*

Protein digestion is initiated in the stomach by pepsin and hydrochloric acid, which denature and break large proteins down to smaller polypeptides. In the small intestine, proteases break down these polypeptides into free amino acids, and di- and tripeptides, which are directly absorbed by the intestinal mucosa.*

Ingredients such as aspergillus oryza, ox bile extract and rennin can also aid in the digestion and absorption of food.*

NOTE: Special Order Product Product - Special Shipping Required
This is a Special Order Product. We stock this in low quantities, due to low-to-moderate sales volume. If the product is on hand, we will ship immediately. If we are out of stock at the time of your order, we will order directly from the manufacturer, on your behalf. This could add an additional 2 to 5 business days to your delivery time.

Supplement Facts Serving Size: One (1) Tablet Servings Per Container: 90

	Amount Per Serving	Daily Value
Betaine (From 60 Mg Betaine HCI)	46 mg	**
Glutamic Acid	10 mg	**
Pancreatin (4X) (equal to 300 mg of Pancreatin)	75 mg	**
Pepsin (1:3,000)	32.5 mg	**
Papain	48 mg	**
Oryza (Aspergillus Oryza)	35 mg	**
Lipase	50 mg	**
Ox Bile Extract	65 mg	**
Rennin	15 mg	**
Malt Diastase	7.5 mg	**
Beet Root Powder	100 mg	**
Citrus Pectin	12.5 mg	**

Myrrh Gum Resin

** Daily Value Not Established. Percent Daily Values are based on a 2,000 calorie diet.

Other Ingredients

Cellulose, Silica, Stearates (Vegetable Source)

Suggested Use

As a dietary supplement, one (1) tablet daily with meals, or more as directed by your physician.

Warnings

Keep out of the reach of children. ... Store in a cool, dry place. ... Do not use if outer seal is missing.

Allergen Info

This product contains NO yeast, wheat gluten, soy protein, milk/dairy, corn, sodium, sugar, starch, preservatives, or artificial coloring/flavoring.

Applicable Functions

Digestive Balance, Metabolism

Related Structure Groups

Digestive System, Fat, Metabolism Function, Pancreas

REFERENCES

Braden B, Picard H, Caspary WF, et al. Monitoring pancreatin supplementation in cystic fibrosis patients with the 13C-Hiolein breath test: evidence for normalized fat assimilation with high dose pancreatin therapy. Z Gastroenterol 1997;35:123-9.

Bragelmann R, Armbrecht U, Rosemeyer D, et al. The effect of pancreatic enzyme supplementation in patients with steatorrhoea after total gastrectomy [see comments]. Eur J Gastroenterol Hepatol 1999;11:231-7.

Gan KH, Heijerman HG, Geus WP, et al. Comparison of a high lipase pancreatic enzyme extract with a regular pancreatin preparation in adult cystic fibrosis patients. Aliment Pharmacol Ther 1994;8:603-7.

Greenberger NJ. Enzymatic therapy in patients with chronic pancreatitis. Gastroenterol Clin North Am 1999;28:687-93. Kalivianakis M, Minich DM, Bijleveld CM, et al. Fat malabsorption in cystic fibrosis patients receiving enzyme replacement therapy is due to impaired intestinal uptake of longchain fatty acids. Am J Clin Nutr 1999;69:127-34.

Layer P, Keller J. Pancreatic enzymes: secretion and luminal nutrient digestion in health and disease. J Clin Gastroenterol 1999;28:3-10. Neoptolemos JP, Ghaneh P, Andren-Sandberg A, et al. Treatment of pancreatic exocrine insufficiency after pancreatic resection. Results of a randomized, double-blind, placebo-controlled, crossover study of high vs standard dose pancreatin. Int J Pancreatol 1999;25:171-80.

Suarez F, Levitt MD, Adshead J, et al. Pancreatic supplements reduce symptomatic response of healthy subjects to a high fat meal. Dig Dis Sci 1999;44:1317-21.

Taylor CJ, Hillel PG, Ghosal S, et al. Gastric emptying and intestinal transit of pancreatic enzyme supplements in cystic fibrosis. Arch Dis Child 1999;80:149-52.

Van Hoozen CM, Peeke PG, Taubeneck M, et al. Efficacy of enzyme supplementation after surgery for chronic pancreatitis. Pancreas 1997;14:174-80.

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