| Neil E. Levin, CCN, DANLA 8/8/05 LIKELY USERS: People looking for joint support; People looking for bone density support; People who want to normalize Vitamin D levels KEY INGREDIENTS: FruiteX-B™ STRUCTURE/FUNCTION CLAIMS: Boron is an important trace mineral for bone and joint health throughout life, as well as for the development and maintenance of healthy bone density. 1,2,4,6,8,9
NOW® OsteoBoron™ is a patented (US Patent # 5,962,049) complex of Boron and Fructose that is safe and more bioavailable than other forms of Boron. 3,7
NOW® OsteoBoron™ is a superior form of Boron that has been the subject of clinical studies demonstrating its efficacy in the support of healthy joints. 7,10
NOW® OsteoBoron™ has also been shown to be safer than other Boron supplements. 3,7 ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: FruiteX-B™ is a patented ingredient that contains boron in a form that is chemically identical to the natural plant forms of boron found in food (Calcium Fructoborate). In human and animal studies this patented form of boron, taken at an amount equal or equivalent to 6 mg. per day, improved bone ash (bone minerals) and Vitamin D status in Vitamin D deficient subjects. In human studies, measurements of joint discomfort were dramatically reduced when taking this dosage for about 2 months. The dose used in most of these studies was equivalent to 2 capsules a day of NOW® OsteoBoron™, a form that has been shown to be biologically more beneficial than other forms of boron.11 SERVING SIZE & HOW TO TAKE IT: One vegetarian capsule twice a day, preferably at separate meals. This dose can be doubled for people with more severe deficiencies, though a physician should normally be consulted in such cases. COMPLEMENTARY PRODUCTS: Vitamin D, Calcium, Magnesium, copper, Silica/silicon, natural sources of phytoestrogens (plant sourced), Ipriflavone, Bone Strength or Bone Calcium formulas CAUTIONS: SPECIFIC: Please note any supplements currently consumed which may also contain boron, such as multiple mineral or multiple vitamin formulas, and cut your serving size of NOW® OsteoBoron™ to compensate. People who eat a lot of produce, fruit and nuts may also get a substantial amount from their food and may want to reduce their servings of NOW® OsteoBoron™ accordingly. NOW® OsteoBoron™ is safer (has less toxicity) than boron citrate. Boron may buffer body levels of estrogen, so women at risk from high estrogen should consult a physician before using NOW® OsteoBoron™, even though this problem has not been noted for food source borons. GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This document has not been reviewed by the FDA or by the company posting it. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time. Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. REFERENCES:
1. Shils ME, Olson JA, Shike M (eds.) (1994) Modern Nutrition in Health and Disease, Eighth Edition. Chapters 20-26, 28, 30. Lea & Febiger Philadelphia.
2. Chang EB, Sitrin MD, Black DD (1996) Gastrointestinal, Hepatobiliary, and Nutritional Physiology. Chapter 9, Absorption of Water-Soluble Vitamins and Minerals. Lippincott-Ravin, Philadelpia
3. Miljkovic D (1999) Boron and carbohydrate complexes and uses thereof. U.S. Patent # 5,962,049. 4. Neilson FH (2000) The Emergence of Boron as Nutritionally Important Throughout the Life Cycle. Nutrition 16(7/8):512-514.
5. Schaafsma A, de Vries PJ, Saris WH (2001) Delay of natural bone loss by higher intakes of specific minerals and vitamins. Crit Rev Food Sci Nutr 41(4):225-249.
6. Devirian TA, Volpe SL (2003) The physiological effects of dietary boron. Crit Rev Food Sci Nutr 43(2):219-213.
7. Miljkovic ND, Miljkovic DA, Ercegan GM (2002) Osteoarthritis and Calcium Fructoborate Supplementation: An Open-Label Study. FutureCeuticals Internal Study.
8. Sheng MH-C, Taper J, Veit H, Qian H, Ritchey SJ, Lau K-H W (2001) Dietary Boron Supplementation Enhanced the Action of Estrogen, But Not that of Parathyroid Hormone, to Improve Trabecular Bone Quality in Ovariectomized Rats. Biol Trace Elem Res 81:29-45. 9. Naghii MR, Samman S (1997) The effect of boron supplementation on its urinary excretion and selected cardiovascular risk factors in healthy male subjects. Biol Trace Elem Res 56(3):273-286. 10. Travers RL, Rennie GC, Newnham RE (1990) Boron and Arthritis: The Results of a Double-Blind Pilot Study. Journal of Nutritional Medicine 1:127-132. 11. Periasamy M, et al. (2001) J Org Chem, 66, 3328-3833 |
