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Douglas Labs

Opti-Zinc
by Douglas Labs
100 Tablets

Zinc Momomethionine Antioxidants For Immune Support*

Our Price: $7.60

OptiZinc tablets, provided by Douglas Laboratories, supply zinc monomethionine, a chemically defined, patented organic compound which provides zinc and the amino acid methionine in a 1:1 ratio. Each scored tablet contains 30 mg of elemental zinc, exclusively in the form of zinc monomethionine.

FUNCTIONS
Zinc is an essential trace element involved in most major metabolic pathways. General signs of human zinc deficiency indicate that zinc has important functions in maintaining immune function, reproduction, healthy skin, and growth.

Numerous studies support the fundamental role of zinc for normal immune response in humans. Immune cells must be able to rapidly divide in order to respond to daily challenges. Like all rapidly dividing cells, immune cells depend on adequate amounts of dietary zinc.

As a cofactor of the antioxidant enzyme superoxide dismutase (SOD), zinc can be considered an antioxidant nutrient. Zinc supplementation has been shown to increase the antioxidant activity of SOD, and provide increased free radical protection. Zinc deficiency is associated with increased oxidative damage.

Absorption of toxic heavy metals, especially cadmium and lead, is lower in individuals with high zinc status compared to those with low zinc status. The body pool of readily available zinc appears to be small, which renders the body susceptible to deficiency and therefore dependent on a steady dietary supply of bioavailable zinc. While typical zinc intakes in U.S. adults are between 10 and 15 mg per day, which approach the RDA, intakes in the elderly are often low. Pregnant women are also at risk for zinc deficiency, since they have a higher requirement for this trace element. Frequently, vegetarians and chronically depressed individuals have been found to have low zinc status. Human and animal studies show that zinc monomethionine, as supplied by OptiZinc, is absorbed and retained better than many other forms of zinc.

Supplement Facts Serving Size: One (1) Tablet Servings Per Container: 100

	Amount Per Serving	Daily Value
Zinc (Zinc Monomethionine)	30 mg	200%

OptiZinc is a trademark of InterHealth Company.

** Daily Value Not Established. Percent Daily Values are based on a 2,000 calorie diet.

Other Ingredients

Cellulose, Magnesium Stearate, Stearic Acid

Suggested Use

As a dietary supplement, one (1) tablet daily or more as directed by physician. Scored tablets may be broken in half for intake adjustment.

Warnings

Store in a cool, dry place, away from direct light. ... No adverse effects have been reported. ... Keep out of reach of children.

Applicable Functions

Cell Formation, Cell Vitality, Growth Normalization, Immune Deficiency, Immune System Support, Skin Conditions

Related Structure Groups

Cell, Cellular Function, Skin

References

Abdallah SM, Samman S. The effect of increasing dietary zinc on the activity of superoxide dismutase and zinc concentration in erythrocytes of healthy female subjects. Eur J Clin Nutr 1993;47:327-332.

Brignola C, Belloli C, De Simone G, et al. Zinc supplementation restores plasma concentrations of zinc and thymulin in patients with Crohn's disease. Aliment Pharmacol Ther 1993;7:275-280.

Chirase NK, Hutcheson DP, Thompson GB. Feed intake, rectal temperature, and serum mineral concentrations of feedlot cattle fed zinc oxide or zinc methionine and challenged with infectious bovine rhinotracheitis virus. J Anim Sci 1991;69:4137-4145.

Donovan UM, Gibson RS. Iron and zinc status of young women aged 14 to 19 years consuming vegetarian and omnivorous diets. J Am Coll Nutr 1995;14:463-472.

Flora SJ, Kumar D, Das Gupta S. Interaction of zinc, methionine or their combination with lead at gastrointestinal or post-absorptive level in rats. Pharmacol Toxicol 1991;68:3-7.

Food and Nutrition Board, National Research Council. Recommended Dietary Allowances. 10th ed. Washington, D.C. Douglas Product Data Laboratories National Academy Press, 1989.

Gordeuk VR, Brittenham GM, Hughes M, Keating LJ, Opplt JJ. Highdose carbonyl iron for iron deficiency anemia: a randomized double-blind trial. Am J Clin Nutr 1987;46:1029-1034.

Goyer RA. Nutrition and metal toxicity. Am J Clin Nutr 1995;61 Suppl.646S-650S.

Gupta RK, Bhattacharya SK, Sundar S, Kumar K, Kachhawaha JS, Sen PC. A correlative study of serum zinc and in vivo cell mediated immune status in rheumatic heart disease. Acta Cardiol 1996;47:297-304.

Hong Bin Q, Garfinkel D. The cadmium toxicity hypothesis of aging: A possible explanation for the zinc deficiency hypothesis of aging. Med Hypotheses 1994;42:380-384.

Keen CL, Gershwin ME. Zinc deficiency and immune function. Annu Rev Nutr 1990;10:415-431.

Kidd MT, Qureshi MA, Ferket PR, Thomas LN. Dietary zinc-methionine enhances mononuclear-phagocytic function in young turkeys. Zincmethionine, immunity, and Salmonella. Biol Trace Elem Res 1994;42:217-229.

Kidd MT, Qureshi MA, Ferket PR, Thomas LN. Blood clearance of Escherichia coli and evaluation of mononuclear-phagocytic system as influenced by supplemental dietary zinc methionine in young turkeys. Poult Sci 1994;73:1381-1389.

King JC, Keen CL. Zinc. In: Shils ME, Olson JA, Shike M, eds. Modern Nutrition in Health and Disease. 8th ed. Philadelphia: Lea & Febiger,1994:214-230.

Maes M, D'Haese PC, Scharpé S, D'Hondt P, Cosyns P, De Broe ME. Hypozincemia in depression. J Affect Disord 1994;31:135-140.

Mares-Perlman JA, Subar AF, Block G, Greger JL, Luby MH. Zinc intake and sources in the US adult population: 1976- 1980. J Am Coll Nutr 1995;14:349-357.

Mei W, Dong ZM, Liao BL, Xu HB. Study of immune function of cancer patients influenced by supplemental zinc or selenium-zinc combination. Biol Trace Elem Res 1991;28:11-19.

Olin KL, Golub MS, Gershwin ME, Hendrickx AG, Lonnerdal B, Keen CL. Extracellular superoxide dismutase activity is affected by dietary zinc intake in nonhuman primate and rodent models. Am J Clin Nutr 1995;61:1263-1267.

Oteiza PI, Olin KL, Fraga CG, Keen CL. Zinc deficiency causes oxidative damage to proteins, lipids and DNA in rat testes. J Nutr 1995;125:823-829.

Prasad AS. Zinc: an overview. Nutrition 1995;11:93-99.

Prasad AS, Fitzgerald JT, Hess JW, Kaplan J, Pelen F, Dardenne M. Zinc deficiency in elderly patients. Nutrition 1993;9:218-224.

Roebothan BV, Chandra RK. Nutrient consumption and body size in a group of institutionalized elderly. Nutr Res 1994;14:35-39.

Sherman AR. Zinc, copper, and iron nutriture and immunity. J Nutr 1992;122:604-609.

Singh A, Failla ML, Deuster PA. Exercise-induced changes in immune function: Effects of zinc supplementation. J Appl Physiol 1994;76:2298-2303.

Small SP, Best DG, Hustins KA. Energy and nutrient intakes of independently-living, elderly women. Can J Nurs Res 1994;26:71-81.

Wedekind KJ, Hortin AE, Baker DH. Methodology for assessing zinc bioavailability: efficacy estimates for zinc-methionine, zinc sulfate, and zinc oxide. J Anim Sci 1992;70:178-187.

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