 |
Ocutone
by Douglas Labs
90 Vegetarian Capsules
Comprehensive Nutritional Support For Healthy Eyes*
| Our Price: $44.30 | 
|
OcuTone, provided by Douglas Laboratories, is a dietary supplement providing a well-balanced spectrum of key nutrients that are important in maintaining normal eye function. OcuTone delivers generous amounts of lutein, beta-carotene, flavonoids, glutathione, sulfur-containing amino acids, trace elements and a comprehensive array of antioxidant vitamins.*
More than any other tissue in the body, the ocular lens and retina are continually exposed to oxygen and intense light radiation. Both light and oxygen can create free radicals that play havoc with lipids in the membranes of visual cells. Experts believe that the uncontrolled generation of free radicals in the eyes can ultimately lead to macular degeneration and cataracts. Therefore, ocular tissues rely on a strong antioxidant defense system to protect them from free radical damage. *
OcuTone was formulated to provide a comprehensive combination of antioxidant nutrients that research has found to be important for proper eye nutrition. OcuTone includes nutritionally meaningful amounts of lutein, beta carotene, antioxidant vitamins, the trace elements zinc and selenium, the cellular antioxidants glutathione and N-Acetyl-L-Cysteine, the amino acid taurine, and potent flavonoids from bilberries and grape seeds. *
Lutein is a carotenoid similar to beta-carotene. Recent research has shown that lutein is the major eye pigment of the outer retina. Lutein is especially
concentrated in the rods, which are the visual cells of the retina that are responsible for black and white vision in the dark. The rods contain complex membranes rich in polyunsaturated fatty acids that are especially susceptible
to lipid peroxidation and free radical damage. Lutein is a potent antioxidant, and researchers believe that the rods require it to protect themselves from light-induced free radical damage. *
Lutein occurs naturally in the diet, especially in dark green leafy vegetables, broccoli and kale. Most people derive about 1 to 2 mg of lutein daily from their diets. Epidemiological studies have shown that daily lutein intakes of 5 to 15 mg may be more appropriate for maintaining normal eye function during aging. As a result, OcuTone was formulated to provide 15 mg of natural lutein complex daily in three capsules. *
Beta-Carotene serves at least two purposes for the eyes. It is a valuable precursor for vitamin A which functions in the rod cells as a light receptor. Beta-Carotene is also an important antioxidant in the lens and retina. OcuTone delivers 12 mg of beta carotene daily to ensure a reliable supply of this important eye nutrient. *
Vitamins C and E. The healthy ocular lens is rich in the antioxidant vitamins C and E, which scavenge oxygenand light-induced free radicals. In the lens, excessive free radicals can lead to protein oxidation and polymerization,
resulting in opaque, cloudy precipitates. High levels of vitamins C and E, and other natural antioxidant defensesystems appear to be necessary for complete protection of the delicate, highly transparent lens proteins. OcuTone provides 500 mg of vitamin C and 400 I.U. of natural vitamin E as d-alpha-tocopherol succinate. *
Zinc is essential for normal visual signal transduction in the retina. Zinc is part of many of the enzymes involved in vitamin A-dependent light reactions in the rod cells. Moreover, zinc is an essential cofactor of superoxide dismutase, an antioxidant enzyme that removes potentially dangerous superoxide radicals in the visual cells, the lens, and other tissues. OcuTone provides 6 mg of zinc in the highly bioavailable monomethionine form. *
Selenium is the essential cofactor of the antioxidant enzyme glutathione peroxidase, which is abundant in healthy eyes. Glutathione peroxidase levels,
however, decline with advancing age, and experts believe that adequate selenium nutrition can help maintain normal production of this important enzyme. OcuTone provides 50 mcg of Selenium, which is roughly equivalent to the required daily amount. *
Glutathione and N-Acetyl-L-Cysteine. Glutathione is the essential cosubstrate for glutathione peroxidase. To carry out its antioxidant functions, this enzyme requires a steady supply of glutathione. In addition, glutathione by itself protects the proteins in the lens from becoming insoluble and cloudy. Although well absorbed, dietary glutathione can not enter the cell, and exerts much of its
beneficial antioxidant effects in the extracellular space. *
NAcetyl-L-Cysteine (NAC) easily enters the cell and is used to synthesize intracellular glutathione. NAC also appears to have antioxidant properties by itself. Many studies have shown that ocular glutathione levels decline as we age. Dietary supplementation with both glutathione and NAC may help maintain normal extracellular and intracellular glutathione levels. Therefore, OcuTone combines a significant 50 mg of glutathione with 300 mg of NAC. *
Taurine, a conditionally-essential sulfur amino acid, is the most abundant free amino acid in ocular tissues, where it may function as a membrane stabilizer,
antioxidant, osmotic regulator, and neurotransmitter. Taurine is important in maintaining normal extra- and intracellular distribution of calcium. This in turn has implications forn euronal excitability and the regulation of osmotic pressure. OcuTone provides 300 mg of pure taurine. *
Bilberry Extract. Bilberries (Vaccinium myrtillus), a northern European cousin of North American blueberries, are a rich source of anthocyanosides, a class of flavonoids recognized for their importance in eye health. Bilberry anthocyanosides are potent antioxidants in the visual cells of the retina, and help maintain normal blood flow in the fine capillary blood vessels that nourish the eyes and other tissues. Three capsules of OcuTone contain 60 mg of a standardized 25 % anthocyanoside extract made from ripe Swedish bilberries.*
Grape Seed Extract. Grape seed extract is rich in proanthocyanidins, another group of important flavonoids. Proanthocyanidins are highly regarded for their strong antioxidant properties and their role in supporting the body’s capillary blood vessel system. Three capsules of OcuTone provide 50 mg of high quality European grape seed extract (from Vitis vinifera) with a minimum of 92 % proanthocyanidins.*
|
|
Supplement FactsServing Size: Three (3) Vegetarian Capsules
Servings Per Container: 30 | | | | Amount
Per Serving | Daily
Value | Vitamin A
(As Natural Beta Carotene From D. Sallina) | 10,000 IU | 200% | Vitamin C
(L-Ascorbic Acid) | 500 mg | 833% | Vitamin E
(D-Alpha-Tocopheryl Succinate) | 400 IU | 1,333% | Zinc
(As Zinc Monomethionine*) | 6 mg | 40% | Selenium
(As Selenium Amino Acid Complex) | 50 mcg | 71% | | Lutein | 15 mg | ** | N-Acetyl Cysteine
USP | 300 mg | ** | Glutathione
(As L-Glutathione, Reduced) | 50 mg | ** | | Taurine | 300 mg | ** | Bilberry Fruit Extract
(Dry)
min. 25 anthocyanosides | 60 mg | ** | Grape Seed Extract
(Min. 92 Proanthocyanidins) | 50 mg | ** | | | *OptiZincbrand of Methionine-bound Zinc.OptiZinc is a trademark of nterHealth Company. |
** Daily Value Not Established. Percent Daily Values are based on a 2,000 calorie diet. |
|
 |
|
|
| Also contains Cellulose, Vegetable Stearate and Silica. |
| |
| As a dietary supplement, adults takeThree (3) capsules daily with food, or as directed by physician.OcuTone may be taken as a dietary supplement to increase intake of selected nutrients that have special importance for normal eye function.* |
| |
| KEEP OUT OF REACH OF CHILDREN. Store in a cool, dry place, away from direct light. |
| |
| No adverse effects have been reported. This product contains NO yeast, wheat, gluten, soy protein, milk/dairy, corn, sodium, sugar, starch, artificial coloring, preservatives or flavoring. |
|
|
|
| Eye Health |
| |
| Eye, Retina |
| |
Christen WG, Jr. Antioxidants and eye disease. Am J Med 1994;97 Suppl. 3A:14S-17S.
Gerster H. Antioxidant vitamins in cataract prevention. Z Ernahrungswiss 1989;28:56-75.
Handelman GJ, Dratz EA, Reay CC, van Kuijk JG. Carotenoids in the human macula and whole retina. Invest Ophthalmol Vis Sci 1988;29:850-855.
Hankinson SE, Stampfer MJ, Seddon JM, et al. Nutrient intake and cataract extraction in women: a prospective study. BMJ 1992;305:335-339.
Heinamaki AA, Muhonen AS, Piha RS. Taurine and other free amino acids in the retina, vitreous, lens, iris-ciliary body, and cornea of the rat eye. Neurochem Res 1986;11:535-542.
Kamei A. Glutathione levels of the human crystalline lens in aging and its antioxidant effect against the oxidation of lens proteins. Biol Pharm Bull 1993;16:870-875.
Kasuya M, Itoi M, Kobayashi S, Sunaga H, Suzuki KT. Changes of glutathione and taurine concentrations in lenses of rat eyes induced by galactose-cataract formation or aging. Exp Eye Res 1992;54:49-53.
Knekt P, Heliovaara M, Rissanen A, Aromaa A, Aaran RK. Serum antioxidant vitamins and risk of cataract. BMJ 1992;305:1392-1394.
Malone JI, Benford SA, Malone J, Jr. Taurine prevents galactose-induced cataracts. J Diabetes Complications 1993;7:44-48.
Mares-Perlman JA, Brady WE, Klein BE, et al. Serum carotenoids and tocopherols and severity of nuclear and cortical opacities. Invest Ophthalmol Vis Sci 1995;36:276-288.
Nakamori K, Koyama I, Nakamura T, et al. Quantitative evaluation of the effectiveness of taurine in protecting the ocular surface against oxidant. Chem Pharm Bull (Tokyo) 1993;41:335-338.
Newsome DA, Swartz M, Leone NC, Elston RC, Miller E. Oral zinc in macular degeneration. Arch Ophthalmol 1988;106:192-198.
Rathbun WB, Schmidt AJ, Holleschau AM. Activity loss of glutathione synthesis enzymes associated with human subcapsular cataract. Invest Ophthalmol Vis Sci 1993;34:2049-2054.
Reddy VN. Glutathione and its function in the lens--an overview. Exp Eye Res 1990;50:771-778.
Schalch W. Carotenoids in the retina--a review of their possible role in preventing or limiting damage caused by light and oxygen. EXS 1995;62:280-298.
Seddon JM, Ajani UA, Sperduto RD, et al. Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular degeneration. Eye Disease Case-Control Study Group. JAMA 1994;272:1413-1420.
Seddon JM, Christen WG, Manson JE, et al. The use of vitamin supplements and the risk of cataract among US male physicians. Am J Public Health 1994;84:788-792.
Sperduto RD, Hu TS, Milton RC, et al. The Linxian cataract studies. Two nutrition intervention trials. Arch Ophthalmol 1993;111:1246-1253.
Taylor A. Associations between nutrition and cataract. Nutr Rev 1989;47:225-234 .
Varma SD. Scientific basis for medical therapy of cataracts by antioxidants. Am J Jlin Nutr 1991;53:335S-345S.
Vitale S, West S, Hallfrisch J, et al. Plasma antioxidants and risk of cortical and nuclear cataract. Epidemiology 1993;4:195-203.
Xie PY, Kanai A, Nakajima A, Kitahara S, Ohtsu A, Fujii K. Glutathione and glutathione related enzymes in human cataractous lenses. Ophthalmic Res 1995;23:133-140.
Zhang WZ, Augusteyn RC. Ageing of glutathione reductase in the lens. Exp Eye Res 1994;59:91-95. |
| |
| ProductData |
 |
Our Price: $44.30 |
|
|
|
|
