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Nutri-E 400
Nutri-E 400
by Douglas Labs
100 Softgels

Antioxidant Supports For Immune System And Cardiovascular Health*

Our Price: $32.30Add to Cart
SKU: DL7059-100X

Nutri-E 400 by Douglas Laboratories contains 400 I.U. of 100% pure, natural, unesterified vitamin E (d-alpha- tocopherol), plus other mixed tocopherols including beta, gamma and delta tocopherols, which assure superior anti-oxidant protection, along with all the synergism associated with 100% natural vitamin E complex.* No synthetic vitamin E is used.

FUNCTIONS
Vitamin E is the collective term for four fat-soluble, natural compounds with similar chemical structure: alpha-, beta-, gamma-, and delta-tocopherol. Of these, alpha-tocopherol has the highest nutritional activity. Eight structural isomers of alpha-tocopherol are possible, but only the d-alpha-tocopherol (RRR- alpha-tocopherol) occurs in nature. The other seven isomers have less nutritional activity and are present only in synthetic vitamin E (dl-alpha-tocopherol). Douglas Laboratories’ vitamin E softgels contain only natural isomers of vitamin E, including d-alpha, d-beta, d-gamma, and d-delta tocopherols which assure superior anti-oxidant protection along with all the synergies.

Vitamin E is one of the body’s most important antioxidant nutrients.* Antioxidants protect healthy cells from oxidative and free radical damage. Free radicals are unstable chemicals formed in the body during metabolism or resulting from exposure to environmental sources, such as pollution and cigarette smoke. Free radicals are necessary for energy metabolism and immune function, but in excessive numbers they can attack healthy cells, especially cell membrane lipids and proteins. This, in turn, is thought to contribute to a number of degenerative diseases.*

Vitamin E is an especially valuable antioxidant in the cell membranes, where it prevents oxidation of unsaturated fatty acids by trapping free radicals. This helps stabilize and protect cell membranes, especially red blood cells and tissues sensitive to oxidation, such as the lungs, eyes, and arteries.* Vitamin E also protects the liver and other tissues from the free-radical damage of toxicants, such as mercury, lead, ozone, nitrous oxide, carbon tetrachloride, benzene, cresol, and various drugs.*

Related to its antioxidant properties, vitamin E is important for normal immune function, and many studies show that it prevents lipid peroxidation of blood lipoproteins, such as LDL-cholesterol.*

Intestinal absorption of vitamin E is associated with fat absorption. Some dietary fat must be present for efficient vitamin E absorption to occur. Studies show that natural d-alpha-tocopherol is more efficiently absorbed and has significantly higher bioavailability than synthetic dl-alpha-tocopherol. Once absorbed, vitamin E is transported into the circulatory system via chylomicrons, and then transferred to VLDL, LDL and HDL particles. Tissues slowly accumulate vitamin E from these plasma lipoproteins. Liver and adipose tissues have the highest concentrations, but muscle also accounts for a large proportion of vitamin E stores in the body.



NOTE: Special Order Product Product - Special Shipping Required
This is a Special Order Product. We stock this in low quantities, due to low-to-moderate sales volume. If the product is on hand, we will ship immediately. If we are out of stock at the time of your order, we will order directly from the manufacturer, on your behalf. This could add an additional 2 to 5 business days to your delivery time.
   

Supplement Facts

Serving Size: One (1) Softgel
Servings Per Container: 100
 Amount
Per Serving
Daily
Value
Vitamin E
(As D-alpha-tocopherol)
With mixed tocopherols providing a minimum of :
400 IU 1,333% 
Gamma Tocopherol280 mg ** 
Tocopherols
(Beta And Delta)
40 mg ** 
** Daily Value Not Established. Percent Daily Values are based on a 2,000 calorie diet.
Other Ingredients
Gelatin Capsule, Glycerine, Water
Suggested Use
As a dietary supplement, one (1) capsule daily, or more as directed by your healthcare professional.
Warnings
The safety of oral vitamin E has been demonstrated in doses as high as 3,200 I.U. per day. ... Keep out of reach of children. ... For optimal storage conditions, keep refrigerated with lid tightly sealed after opening. ... Do not use if outer seal is missing.
Allergen Info
This product contains NO yeast, no wheat gluten, no soy protein, no milk/dairy, no corn, no sodium, no sugar, no starch, no preservatives, and no artificial coloring or flavoring.



Applicable Functions
Cell Vitality, Cellular Oxidation, Free Radicals, Immune System Support, Liver Toxicity, Liver Wellness - deep
Related Structure Groups
Cell, Cellular Function, Immune System, Liver, Tissue
REFERENCES

Abbey M. The importance of vitamin E in reducing cardiovascular risk. Nutr Rev 1995;53 Suppl.S28-S32.

Anderson LE, Sr., Myer RO, Brendemuhl JH, McDowell LR. Bioavailability of various vitamin E compounds for finishing swine. J Anim Sci 1995;73:490-495.

Beales PE, Williams AJK, Albertini MC, Pozzilli P. Vitamin E delays diabetes onset in the non-obese diabetic mouse. Horm Metab Res 1994;26:450-452.

Brown KM, Morrice PC, Duthie GG. Vitamin E supplementation suppresses indexes of lipid peroxidation and platelet counts in blood of smokers and nonsmokers but plasma lipoprotein concentrations remain unchanged. Am J Clin Nutr 1994;60:383-387.

Calzada C, Bizzotto M, Paganga G, et al. Levels of antioxidant nutrients in plasma and low density lipoproteins: A human volunteer supplementation study. Free Radic Res 1995;23:489-503.

Carpenter KLH, Cheeseman KH, Van der Veen C, Taylor SE, Walker MK, Mitchinson MJ. Depletion of alpha-tocopherol in human atherosclerotic lesions. Free Radic Res 1995;23:549-558.

Cheeseman KH, Holley AE, Kelly FJ, Wasil M, Hughes L, Burton G. Biokinetics in humans of RRR-a-tocopherol: The free phenol, acetate ester, and succinate ester forms of vitamin E. Free Radic Biol Med 1995;19:591-598.

Das S. Vitamin E in the genesis and prevention of cancer--A review. Acta Oncol 1994;33:615-619.

Dutta-Roy AK, Gordon MJ, Campbell FM, Duthie GG, James WPT. Vitamin E requirements, transport, and metabolism: Role of a-tocopherolbinding proteins. J Nutr Biochem 1994;5:562-570.

Felemovicius I, Bonsack ME, Baptista ML, Delaney JP. Intestinal radioprotection by vitamin E (alpha-tocopherol). Ann Surg 1995;222:504-510.

Flagg EW, Coates RJ, Greenberg RS. Epidemiologic studies of antioxidants and cancer in humans. J Am Coll Nutr 1995;14:419-427.

Friedrichson T, LeVan Kalbach H, Buck P, Van Kuijk FJGM. Vitamin E in macular and peripheral tissues of the human eye. Curr Eye Res 1995;14:693-701.

Hartmann A, Niess AM, Grünert-Fuchs M, Poch B, Speit G. Vitamin E prevents exercise-induced DNA damage. Mutat Res Lett 1995;346:195-202.

Hodis HN, Mack WJ, LaBree L, et al. Serial coronary angiographic evidence that antioxidant vitamin intake reduces progression of coronary artery atherosclerosis. JAMA 1995;273:1849-1854.

Holvoet P, Collen D. Oxidized lipoproteins in atherosclerosis and thrombosis. FASEB J 1994;8:1279-1284.

Jialal I, Fuller CJ, Huet BA. The effect of a-tocopherol supplementation on LDL oxidation: A dose-response study. Arterioscler Thromb 1995;15:190-198.

Knekt P, Reunanen A, Järvinen R, Seppänen R, Heliövaara M, Aromaa A. Antioxidant vitamin intake and coronary mortality in a longitudinal population study. Am J Epidemiol 1994;139:1180-1189.

Knekt P, Heliovaara M, Rissanen A, Aromaa A, Aaran RK. Serum antioxidant vitamins and risk of cataract. BMJ 1992;305:1392-1394.

Konikoff F. The therapeutic benefit of vitamin E in patients with liver disease. J Hepatol 1994;21:687-688.

Luostarinen R,Wallin R, Wibell L, Saldeen T. Vitamin E supplementation counteracts the fish oil-induced increase of blood glucose in humans. Nutr Res 1995;15:953-968.

Meydani SN, Meydani M, Rall LC, Morrow F, Blumberg JB. Assessment of the safety of high-dose, short-term supplementation with vitamin E in healthy older adults. Am J Clin Nutr 1994;60:704-709.

Odeleye OE, Watson RR. The potential role of vitamin E in the treatment of immunologic abnormalities during acquired immune deficiency syndrome. Prog Food Nutr Sci 1991;15:1-19.

Paolisso G, Gambardella A, GI.U.gliano D, et al. Chronic intake of pharmacological doses of vitamin E might be useful in the therapy of elderly patients with coronary heart disease. Am J Clin Nutr 1995;61:848-852.

Princen HMG, Van Duyvenvoorde W, Buytenhek R, et al. Supplementation with low doses of vitamin E protects LDL from lipid peroxidation in men and women. Arterioscler Thromb 1995;15:325-333.

Reiter RJ. Oxidative processes and antioxidative defense mechanisms in the aging brain. FASEB J 1995;9:526-533.

Traber MG, Ramakrishnan R, Kayden HJ. Human plasma vitamin E kinetics demonstrate rapid recycling of plasma RRR-a-tocopherol. Proc Natl Acad Sci USA 1994;91:10005-10008.

Wang Y, Watson RR. Potential therapeutics of vitamin E (tocopherol) in AIDS and HIV. Drugs 1994;48:327-338.

Wang Y, Huang DS, Liang B, Watson RR. Nutritional status and immune responses in mice with murine AIDS are normalized by vitamin E supplementation. J Nutr 1994;124:2024-2032.

Wang Y, Watson RR. Is vitamin E supplementation a useful agent in AIDS therapy? Prog Food Nutr Sci 1993;17:351-375.

Winklhofer-Roob BM, Ziouzenkova O, Puhl H, et al. Impaired resistance to fibrosis: improvement during vitamin E supplementation. Free Radic Biol Med 1995;19:725-733.

Yau TM, Weisel RD, Mickle DAG, et al. Vitamin E for coronary bypass operations: A prospective, double-blind, randomized trial. J Thorac Cardiovasc Surg 1994;108:302-310.

Nutri-E 400 Our Price: $32.30 Add to Cart
SKU: DL7059-100X
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