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Milk Thistle Max-V

Suitable For Vegetarians
Milk Thistle Max-V
by Douglas Labs
60 Vegetarian Capsules

Supports And Enhances Normal, Healthy Liver Function*

Our Price: $21.90Add to Cart
SKU: DL77358-60X

Milk Thistle Max-V vegetarian capsules provided by Douglas Laboratories contain 250 mg of milk thistle extract, standardized to contain a minimum of 200 mg of the flavonoid silymarin.

FUNCTIONS
Milk thistle, a common herb native to the Mediterranean, has been widely used for its nutritional support of liver function for over 2,000 years. Fruits (often mistakenly referred to as seeds) of the dried milk thistle flower are rich in silymarin, a bioflavonoid complex of three flavonolignins: silybin, silydianin, and silychristin. Silymarin is responsible for milk thistle’s powerful protective and regenerative activities in the liver.*

The liver is the body’s detoxifying organ, disabling toxins such as ethanol, environmental poisons, pesticides, and certain pharmaceuticals. In addition to its detoxification properties, the liver plays an essential role in protein, carbohydrate, and lipid metabolism; cholesterol synthesis; bile secretion; and storage of fat-soluble vitamins. When damaged or diseased, the liver’s ability to eliminate toxins and perform its numerous other functions may be severely impaired.

Silymarin has been shown to support and enhance normal, normal, healthy hepatic function through three primary actions:

•Silymarin protects liver cells by blocking hepatotoxic substances from crossing cell membranes by binding to the outer cell membrane.  In this way it serves as an antioxidant, and stimulates cell regeneration.* Silymarin appears effective in protecting the liver from deleterious effects of both acute and chronic toxin exposures, including that of ethanol, hepatotoxic medications such as excessive acetaminophen, poisonous fungi, and environmental pollutants.

•Silymarin further protects the liver as an important component of the liver’s antioxidant defense.* The liver generates potentially damaging, toxic free radicals and reactive oxygen species (e.g., peroxides) as a result of its normal metabolic and detoxifying functions. Left unchecked, these radicals can initiate a chain reaction of lipid peroxidation, causing damage to cell structure and interfering with normal cell functions. Fortunately, silymarin interrupts this course of free radical damage. As an antioxidant, silymarin quenches free radicals, thus protecting against lipid peroxidation.

•Further, silymarin enhances levels of glutathione and superoxide dismutase, two primary antioxidants in the liver.* As a consequence of its antioxidant activities in the liver, silymarin decreases the free radical quenching load of glutathione, thus sparing it from depletion. Similarly, silymarin spares superoxide dismutase in the liver cell, thereby increasing both the amount and activity of superoxide dismutase in both hepatic and red blood cells.*

In addition to its protective functions, silymarin stimulates damaged liver cells to regenerate. In the cell nucleus, silymarin activates ribosomal RNA via RNA polymerase 1, leading to increased production of ribosomes. By augmenting the production of ribosomes, the cell organelle responsible for protein synthesis, silymarin stimulates protein synthesis in the damaged cell. This results in expedited cell regeneration, the replacement and repair of damaged cells.*

Milk Thistle Max-V vegetarian capsules may be a useful nutritional supplement for individuals who wish to enhance healthy hepatic function through the natural protective and regenerative properties of this herb. Milk Thistle may be especially well suited for individuals with excessive or chronic exposure to environmental toxins, pesticides, alcohol, hepatotoxic pharmaceuticals, and other substances damaging to the liver.*


NOTE: Special Order Product Product - Special Shipping Required
This is a Special Order Product. We stock this in low quantities, due to low-to-moderate sales volume. If the product is on hand, we will ship immediately. If we are out of stock at the time of your order, we will order directly from the manufacturer, on your behalf. This could add an additional 2 to 5 business days to your delivery time.
   

Supplement Facts

Serving Size: One (1) Vcaps Vegetarian Capsule
Servings Per Container: 60
 Amount
Per Serving
Daily
Value
Milk Thistle Herbal Extract Blend
(Silybum Marianum)
Standardized to provide 200 mg of silymarin
250 mg ** 
Milk Thistle Seed
(Non-standardized)
100 mg  
** Daily Value Not Established. Percent Daily Values are based on a 2,000 calorie diet.
Other Ingredients
Cellulose, Stearates (Vegetable Source)
Suggested Use
As a dietary supplement, one (1) capsule two (2) times daily between meals, or more as directed by your healthcare professional. If digestive irritation occurs, take with meals. Use continuously for maximum benefit.*
Warnings
Stop use and consult your healthcare professional if allergic reactions occur. ... If you are pregnant or nursing, consult your healthcare professional before using this product. ... Keep out of the reach of children ... Store in a cool, dry place ... Do not use if outer seal is missing.
Allergen Info
This product contains NO yeast, no wheat gluten, no soy protein, no milk/dairy, no corn, no sodium, no sugar, no starch, no preservatives, and no artificial coloring or flavoring.



Applicable Functions
Liver Detoxification, Liver Toxicity, Liver Wellness - deep
Related Structure Groups
Immune System, Liver
REFERENCES

Allain, H, Schuck, S, Lebreton, S, Strenge-Hesse, A, Braun, W, Gandon, JM, Brissot, P. Aminotransferase levels and silymarin inde novo tacrine-treated patients with Alzheimer's disease. Dement Geriatr Cogn Disord 1999;10:181-5.

Bass, NM. Is there any use for nontraditional or alternative therapies in patients with chronic liver disease? [In Process Citation]. Curr Gastroenterol Rep 1999;1:50-6.

Berkson, BM. A conservative triple antioxidant approach to the treatment of hepatitis C. Combination of alpha lipoic acid (thioctic acid), silymarin, and selenium: three case histories. Med Klin 1999;94 Suppl 3:84-9.

Edwards, J, Grange, LL, Wang, M, Reyes, E. Fetoprotectivity of the flavanolignan compound siliphos against ethanol- induced toxicity [In Process Citation]. Phytother Res 2000;14:517-21.

Farghali, H, Kamenikova, L, Hynie, S, Kmonickova, E. Silymarin effects on intracellular calcuim and cytotoxicity: a study in perfused rat hepatocytes after oxidative stress injury. Pharmacol Res 2000;41:231-7.

Flora, K, Hahn, M, Rosen, H, Benner, K. Milk thistle (Silybum marianum) for the therapy of liver disease [see comments]. Am J Gastroenterol 1998;93:139-43.

Kropacova, K, Misurova, E, Hakova, H. Protective and therapeutic effect of silymarin on the development of latent liver damage. Radiats Biol Radioecol 1998;38:411-5.

Par, A, Roth, E, Rumi, G, Jr., Kovacs, Z, Nemes, J, Mozsik, G. [Oxidative stress and antioxidant defense in alcoholic liver disease and chronic hepatitis C]. Orv Hetil 2000;141:1655-9.

Zhao, J, Sharma, Y, Agarwal, R. Significant inhibition by the flavonoid antioxidant silymarin against 12-O-tetradecanoylphorbol 13-acetate-caused modulation of antioxidant and inflammatory enzymes, and cyclooxygenase 2 and interleukin-1alpha expression in SENCAR mouse epidermis: implications in the prevention of stage I tumor promotion. Mol Carcinog 1999;26:321-33.

Zhao, J, Agarwal, R. Tissue distribution of silibinin, the major active constituent of silymarin, in mice and its association with enhancement of phase II enzymes: implications in cancer chemoprevention. Carcinogenesis 1999;20:2101-8.


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Milk Thistle Max-V Our Price: $21.90 Add to Cart
SKU: DL77358-60X
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