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Liver Detoxifier & Regenerator
Liver Detoxifier & Regenerator
by NOW Foods - Digestive Support
90 Capsules

A Proprietary Blend of Herbs and Nutrients Designed to Support Healthy Liver Function*

Our Price: $12.14
Retail Price: $20.98
You Save: $8.84 each, a 42% Savings!
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SKU: 2448NOW


Dr. Verghese's Liver Formula is a proprietary blend of herbs and nutrients designed to support healthy liver function.  Dr. Verghese's Liver Formula contains Milk Thistle Extract, which has been shown in clinical and non-clinical studies to support the liver, as measured by standard liver enzyme laboratory tests.  In addition, Dr. Verghese's Liver Formula contains N-Acetyl Cysteine and Methionine, two amino acids known to enhance the production of glutathione in the liver.  Glutathione, a major cellular antioxidant plays an essential role in liver detoxification mechanisms.  Also included in this Liver Formula are other herbs (Schisandra, Bupleurum, and Scute) that have been developed by Dr. C. Samuel Verghese, M.D. and until now has been used exclusively in this practice.  Dr. Verghese recommends this formula for frequent travellers who want to support their liver health while travelling abroad.*


   

Supplement Facts

Three (3) Capsules Contain: Amount Per Serving
Calories10 
Total Carbohydrates1 g
Dietary Fiber0.7 g
Vitamin C
  (ascorbyl palmitate)
12 mg
Milk Thistle (Silybum marianum)
  (seed)
  Standardized Extract. (min. 80% Silymarin)
300 mg
A Proprietary
  Herbal-Nutrient Blend
250 mg
Artichoke Leaf (Cynara scolymus L.) 
Beet Leaf (Beta vulgaris rubra) 
Bladderwrack Whole Plant 
Raspberry Leaf (Rubus idaeus) 
Phosphatidyl Choline
  (from SOY)
 
Pancreatic Enzyme 
Blue Flag Root (Iris versicolor) 
Cleavers Aerial Parts (Galium aparine) 
L-Glutathione
  (free- form)
100 mg
N-Acetyl Cysteine100 mg
Bupleurum Root (Bupleurum chinense)100 mg
Grape Seed (Vitis vinifera)100 mg
Dandelion (Taraxacum officinale)100 mg
L-Carnitine50 mg
Scute
  (4:1 conc.extract)
50 mg
Pueraria (Pueria thunbergiana)
  (4:1 Conc. Extract)
50 mg
Schisandra (Schisandra chinensis)
  (fruit)
50 mg
Barberry Bark (Berberis vulgaris)30 mg
Turmeric (Curcuma longa)
  (root)
30 mg
L-Methionine20 mg
Greater Celandine Whole Plant (Chelindonium majus)
  (4:1 Conc. Extract)
10 mg
Other Ingredients
Stearic Acid, Silica, Magnesium Stearate, Gelatin Capsule, Cellulose, Contains SOY derivative. Contains no sugar, salt, starch, yeast, wheat, gluten, milk, egg or preservatives.
Suggested Use
As a dietary supplement, three (3) capsules daily with meals, or as directed by a healthcare practitioner.
Warnings
This formula should not be used by pregnant women, nursing mothers children or those with liver problems unless recommended under the supervision of a healthcare professional. Please notify your physician about your supplement use if you are using any drugs.



Related Types
Detoxification
Applicable Functions
Liver Deficiency, Mood Swings, Toxicity
Related Structure Groups
Immune System, Liver, Skin
Related Emotions
Abrasiveness, Angry, Bitter
Dr. Verghese, M.D. Liver Detoxifier & Regenerator Fact Sheet


Neil E. Levin, CCN, DANLA
02/10/05

 
LIKELY USERS: People with exposure to toxins that stimulate liver activity; People with exposure to infections that may have damaged liver tissue
 
KEY INGREDIENT (S): Milk Thistle extract (Silymarin), Glutathione, NAC, Bupleurum extract, Grape Seed Extract, Dandelion Root extract, Artichoke Leaf, Schisandra and about a dozen additional herbs, along with synergistic ingredients
 
MAIN PRODUCT FEATURES:  This formula was developed by a physician based on his clinical experience.
  • Artichoke leaf has antioxidant properties and restores healthy growth to liver cells.
  • Bupleurum may promote normal cell growth, immune function and is a staple of Chinese liver formulas.
  • Dandelion Root may serve as a natural down-regulator of inflammatory chemicals in the body.
  • NAC supports liver Glutathione stores (antioxidant, detoxifier, heavy metal chelator).
  • Schisandra protects liver cells from toxins and may help to regenerate damaged cells.

Milk thistle’s antioxidant Silymarin improves liver function tests and protects liver cells against oxidative damage. It also protects liver cells by blocking and removing toxins from the liver. Silymarin aids in regenerating injured liver cells and blocks fibrosis.

OTHER IMPORTANT ISSUES:

Samuel Verghese, M.D. (AM), Ph.D., BCIA-EEG, DAAPM, holds a degree in Alternative Medicine and specializes in Nutritional, Ayurvedic and other Alternative Health Solutions. He is certified as a BCIA-EEG Associate Fellow.

AMOUNT TO USE: Three or more capsules a day, preferably with meals.

SYNERGISTS: Antioxidants (supports liver detoxification), Alpha Lipoic Acid, EGCg Green Tea Extract, Astragalus, medicinal mushrooms (shiitake, reishi), SAM-e (may improve bile flow and promotes methylation to detoxify chemicals), TMG, lecithin, thymus glandular extract, Cordyceps.

AVOID: acetaminophen, alcohol, iron supplements (also red meat, fortified flour)

CAUTIONS: This formula should not be used by pregnant women, nursing mothers children or those with liver problems unless recommended under the supervision of a healthcare professional. Please notify your physician about your supplement use if you are using any drugs!

REFERENCES:

  1. Salmi HA, Sarna S. Effect of silymarin on chemical, functional and morphological alterations of the liver. A double-blind controlled study. Scand J Gastroenterol 1982;17:517–21.
  2. Feher J, Deak G, Muzes G, et al. Liver-protective action of silymarin therapy in chronic alcoholic liver diseases. Orv Hetil 1989;130:2723–7 [in Hungarian].
  3. Muzes G, Deak G, Lang I, et al. Effect of silymarin (Legalon) therapy on the antioxidant defense mechanism and lipid peroxidation in alcoholic liver disease (double blind protocol.) Orv Hetil 1990:131:863–6 [in Hungarian].
  4. Velussi M, Cernigoi AM, De Monte A, et al. Long-term (12 months) treatment with an anti-oxidant drug (silymarin) is effective on hyperinsulinemia, exogenous insulin need and malondialdehyde levels in cirrhotic diabetic patients. J Hepatol 1997;26:871–9.
  5. Lieber CS. Nutrition in liver disorders. In: Shils ME, Olson JA, Shike M, Ross AC (eds). Modern Nutrition in Health and Disease, 9th ed. Baltimore, MD: Williams and Wilkins, 1999, 1179–80.
  6. Rodriguez-Moreno F, Gonzalez-Reimers E, Santolaria-Fernandez F, et al. Zinc, copper, manganese, and iron in chronic alcoholic liver disease. Alcohol 1997;14:39–44.
  7. Gibbs K, Walshe JM. Studies with radioactive copper (64 Cu and 67 Cu); the incorporation of radioactive copper into caeruloplasmin in Wilson’s disease and in primary biliary cirrhosis. Clin Sci 1971;41:189–202.
  8. Lieber CS. Nutrition in liver disorders. In: Shils ME, Olson JA, Shike M, Ross AC (eds). Modern Nutrition in Health and Disease, 9th ed. Baltimore, MD: Williams and Wilkins, 1999:1179–80.
  9. Halsted CH. Alcohol: medical and nutritional effects. In Ziegler EE, Filer LJ (eds). Present Knowledge in Nutrition, 7th ed. ILSI Press, Washington, DC, 1996, 553.
  10. Blum AL, Doelle W, Kortum K, et al. Treatment of acute viral hepatitis with (+)-cyanidanol-3. Lancet 1977;2:1153–5.
  11. Suzuki H, Yamamoto S, Hirayama C, et al. Cianidanol therapy for HBs-antigen-positive chronic hepatitis: a multicentre, double-blind study. Liver 1986;6:35–44.
  12. Tang W, Eisenbrand G. Chinese Drugs of Plant Origin. Berlin: Springer Verlag, 1992. (Astragalus)
  13. Hobbs, C. Medicinal Mushrooms. Santa Cruz, CA: Botanica Press, 1995, 96–107.
  14. Harada T, Kanetaka T, Suzuki H, Suzuki K. Therapeutic effect of LEM (extract of cultured Lentinus edodes mycelia) against HBeAg-positive chronic hepatitis B. Gastroenterol Int 1988;1(suppl 1):abstract 719.
  15. Kelly GS. Clinical applications of N-acetylcysteine. Altern Med Rev. Apr1998;3(2):114-27.
  16. Montanini S, et al. Use of acetylcysteine as the life-saving antidote in Amanita phalloides (death cap) poisoning. Case report on 11 patients. Arzneimittelforschung. Dec1999;49(12):1044-7.
  17. Buckley NA, et al. Oral or intravenous N-acetylcysteine: which is the treatment of choice for acetaminophen (paracetamol) poisoning? J Toxicol Clin Toxicol. 1999;37(6):759-67.
  18. Girardi G, Elias MM. Effectiveness of N-acetylcysteine in protecting against mercuric chloride-induced nephrotoxicity. Toxicology. Apr1991;67(2):155-64.
  19. Berkson MB. Alpha-Lipoic Acid (Thioctic Acid): My Experience With This Outstanding Therapeutic Agent. Journal of Orthomolecular Medicine. 1998;13(1):44-48.
  20. Breithaupt-Grogler K, et al. Dose-proportionality of oral thioctic acid--coincidence of assessments via pooled plasma and individual data. Eur J Pharm Sci. Apr1999;8(1):57-65.
  21. Gebhardt R. Antioxidative and Protective Properties of Extracts from Leaves of the Artichoke (Cynara scolymus L.) Against Hydroperoxide-induced Oxidative Stress in Cultured Rat Hepatocytes. Toxicol Appl Pharmacol. Jun1997;144(2):279-86.
  22. Adzet T, et al. Hepatoprotective Activity of Polyphenolic Compounds From Cynara scolymus Against CCl4 Toxicity in Isolated Rat Hepatocytes. J Nat Prod. Jul1987;50(4):612-17.
  23. Gebhardt R. Antioxidative and protective properties of extracts from leaves of the artichoke (Cynara scolymus L.) against hydroperoxide-induced oxidative stress in cultured rat hepatocytes. Toxicol Appl Pharmacol. Jun1997;144(2):279-86.
  24. Khadzhai I, et al. Effect of Artichoke Extracts on the Liver. Farmakol Toksikol. Nov1971;34(6):685-87.
  25. Newall CA, et al. Herbal Medicine: A Guide for Health-Care Professionals. Cambridge: Pharmaceutical Press; 1996:36-37.
  26. Newall CA, et al. Herbal Medicines: A Guide for Health Care Professionals. London: The Pharmaceutical Press;1996:96-97.
  27. Bradley PR, ed. British Herbal Compendium. Vol.1. Bournemouth: British Herbal Medicine Association;1992:73-74.
  28. Newall CA, et al. Herbal Medicines: A Guide for Health Care Professionals. London: The Pharmaceutical Press;1996:96-97.

NOW Quality
 

Raw Materials

Superior supplements begin with superior raw materials. As the foundation that supports our line of quality products, NOW tests raw materials for contaminants, heavy metals, pesticides and fillers. Our philosophy remains unfaltering; we always start with the purest, freshest raw materials to ensure that the finished product is the best it can be. By partnering with some of the most trusted names in the industry including Lonza, PL Thomas, Cyanotech, Inter-Health, Hoffman LaRoche, Sabinsa and others, NOW is proud to provide unadulterated natural products that are safe, potent and true to their claim.

  • Natural Ingredients
  • Mad Cow Free
  • Growth Hormone Free
  • Exacting Heavy Metal and Pesticide Specifications
  • Pure, Fresh Raw Materials, Always

Good Manufacturing Practices

NOW's commitment to Good Manufacturing Practice (GMP) is evident in everything we do. As one of the first companies to receive GMP certification from the NNFA, in addition to being one of the very few to maintain a consistent 'A' rating, we've remained steadfast in our commitment to good manufacturing practices. Our clean, controlled and technologically advanced production facility is regularly inspected by the Food and Drug Administration, and has been certified organic by Quality Assurance International.

  • Longstanding NNFA GMP "A" Rating
  • FDA Inspected
  • Organic Certification by QAI
  • Clean, Modern, Controlled Production Facility
Liver Detoxifier & Regenerator Our Price: $12.14
Retail Price: $20.98
You Save: $8.84 each, a 42% Savings!
Add to Cart
SKU: 2448NOW
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