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L-Arginine 500 Mg.
by Douglas Labs
60 Capsules
A Versatile, Conditionally Essential Amino Acid
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L-Arginine capsules, provided by Douglas Laboratories, contain 500 mg pure, crystalline L- arginine. Arginine assists growth hormone metabolism. It is usually made by the body in sufficient amounts but an increased need for arginine may occur in times of high protein demand.*
FUNCTIONS
Amino acids have many functions in the body. They are the building blocks for all body proteins — structural proteins that build muscle, connective tissues, bones and other structures, and functional proteins in the form of thousands of metabolically active enzymes. Amino acids provide the body with the nitrogen that is essential for growth and maintenance of all tissues and structures. Aside from these general functions, individual amino acids also have specific functions in many aspects of human physiology and biochemistry.*
L-arginine is a conditionally essential dibasic amino acid. The body is usually capable of producing sufficient amounts of arginine, but in conditions of physical stress, e.g., trauma or illness, endogenous synthesis is often inadequate to meet the body’s increased demands. L-arginine can be either used for glucose synthesis or catabolized to produce energy via the tricarboxylic acid cycle. It is needed for tissue protein synthesis and ammonia detoxification via the urea acid cycle.* It is needed for tissue protein synthesis and ammonia detoxification via the urea acid cycle.*
As a precursor of nitric oxide, L-arginine may ameliorate the negative smoking-induced changes to the structure and function of vascular tissue. L-arginine is required for the synthesis of creatine phosphate. Similar to adenosine triphosphate (ATP), creatine phosphate functions as a carrier of readily available energy for contractile work in muscles.* Adequate reservoirs of creatine phosphate are necessary in muscle as an energy reserve for anaerobic activity.
L-arginine is also a precursor of polyamines, including putrescine, spermine and spermidine. Spermine and spermidine interact with DNA, act as physiological growth regulators of cell proliferation, and are involved in the stabilization of cell membranes and cell organelles. L-arginine is a potent stimulator of insulin, glucagon, and growth hormone release, and functions as a representative signal to the endocrine system that dietary protein ingestion has taken place.*
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NOTE: Special Order Product Product - Special Shipping Required
This is a Special Order Product. We stock this in low quantities, due to low-to-moderate sales volume. If the product is on hand, we will ship immediately. If we are out of stock at the time of your order, we will order directly from the manufacturer, on your behalf. This could add an additional 2 to 5 business days to your delivery time. |
Supplement FactsServing Size: One (1) Capsule
Servings Per Container: 60 | | | | Amount
Per Serving | Daily
Value | | L-Arginine | 500 mg | ** | |
** Daily Value Not Established. Percent Daily Values are based on a 2,000 calorie diet. |
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| Cellulose, Gelatin Capsule, Stearates (Vegetable Source) |
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| As a dietary supplement for adults, one (1) capsule per day, or more as directed by your healthcare professional. It is recommended that this product be taken in conjunction with vitamins and minerals. |
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| Keep out of the reach of children. ... Store in a cool, dry place. ... Do not use if outer seal is missing. |
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| This product contains NO yeast, wheat gluten, soy protein, milk/dairy, corn, sodium, sugar, starch, preservatives, or artificial coloring/flavoring. |
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| Amino acid deficiency, Protein Energy Malnutrition |
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| Amino Acids, Bones, Connective Tissue, Muscles, Tissue |
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Arvat E, Gianotti L, Grottoli S, Imbimbo BP, Lenaerts V, Deghenghi R, Camanni F, Ghigo E. Arginine and growth hormone-releasing hormone restore the blunted growth hormone-releasing activity of hexarelin in elderly subjects. J Clin Endocrinol Metab 1994;79:1440-3.
Bellone J, Bartolotta E, Cardinale G, Arvat E, Cherubini V, Aimaretti G, Maccario M, Mucci M, Camanni F, Ghigo E. Low dose orally administered arginine is able to enhance both basal and growth hormone-releasing hormone-induced growth hormone secretion in normal short children. J Endocrinol Invest 1993;16:521-5.
Bode-Boger SM, Boger RH, Galland A, Tsikas D, Frolich JC. Larginine-induced vasodilation in healthy humans: pharmacokineticpharmacodynamic relationship. Br J Clin Pharmacol 1998;46:489-97.
Bode-Boger SM, Boger RH, Kienke S, Bohme M, Phivthong-ngam L, Tsikas D, Frolich JC. Chronic dietary supplementation with L-arginine inhibits platelet aggregation and thromboxane A2 synthesis in hypercholesterolaemic rabbits in vivo. Cardiovasc Res 1998;37:756-64.
Boger RH, Bode-Boger SM, Phivthong-ngam L, Brandes RP, Schwedhelm E, Mugge A, Bohme M, Tsikas D, Frolich JC. Dietary Larginine and alpha-tocopherol reduce vascular oxidative stress and preserve endothelial function in hypercholesterolemic rabbits via different mechanisms. Atherosclerosis 1998;141:31-43.
Boger RH, Bode-Boger SM, Thiele W, Creutzig A, Alexander K, Frolich JC. Restoring vascular nitric oxide formation by L-arginine improves the symptoms of intermittent claudication in patients with peripheral arterial occlusive disease. J Am Coll Cardiol 1998;32:1336-44.
Bower RH, Cerra FB, Bershadsky B, Licari JJ, Hoyt DB, Jensen GL, Van Buren CT, Rothkopf MM, Daly JM, Adelsberg BR. Early enteral administration of a formula (Impact) supplemented with arginine, nucleotides, and fish oil in intensive care unit patients: results of a multicenter, prospective, randomized, clinical trial [see comments]. Crit Care Med 1995;23:436-49.
Candipan RC, Wang BY, Buitrago R, Tsao PS, Cooke JP. Regression or progression. Dependency on vascular nitric oxide. Arterioscler Thromb Vasc Biol 1996;16:44-50.
Cynober L. Can arginine and ornithine support gut functions? Gut 1994;35:S42-5.
De Bandt JP, Cynober L, Lim SK, Coudray-Lucas C, Poupon R, Giboudeau J. Metabolism of ornithine, alpha-ketoglutarate and arginine in isolated perfused rat liver. Br J Nutr 1995;73:227-39.
Dumas F, De Bandt JP, Colomb V, Le Boucher J, Coudray-Lucas C, Lavie S, Brousse N, Ricour C, Cynober L, Goulet O. Enteral ornithine alpha-ketoglutarate enhances intestinal adaptation to massive resection in rats. Metabolism 1998;47:1366-71.
Ghigo E, Arvat E, Rizzi G, Bellone J, Nicolosi M, Boffano GM, Mucci M, Boghen MF, Camanni F. Arginine enhances the growth hormonereleasing activity of a synthetic hexapeptide (GHRP-6) in elderly but not in young subjects after oral administration. J Endocrinol Invest 1994;17:157-62.
Ghigo E, Miola C, Aimaretti G, Valente F, Procopio M, Arvat E, Yin- Zhang W, Camanni F. Arginine abolishes the inhibitory effect of glucose on the growth hormone response to growth hormone-releasing hormone in man. Metabolism 1992;41:1000-3.
Gurbuz AT, Kunzelman J, Ratzer EE. Supplemental dietary arginine accelerates intestinal mucosal regeneration and enhances bacterial clearance following radiation enteritis in rats. J Surg Res 1998;74:149-54.
Hebiguchi T, Kato T, Yoshino H, Mizuno M, Koyama K. The effect of arginine supplementation on growth hormone release and intestinal mucosal growth after massive small bowel resection in growing rats. J Pediatr Surg 1997;32:1149-53.
Hutchison SJ, Sudhir K, Sievers RE, Zhu BQ, Sun YP, Chou TM, Chatterjee K, Deedwania PC, Cooke JP, Glantz SA, Parmley WW. Effects of L-arginine on atherogenesis and endothelial dysfunction due to secondhand smoke. Hypertension 1999;34:44-50.
Moinard C, Chauveau B, Walrand S, Felgines C, Chassagne J, Caldefie F, Cynober LA, Vasson MP. Phagocyte functions in stressed rats: comparison of modulation by glutamine, arginine and ornithine 2- oxoglutarate [In Process Citation]. Clin Sci (Colch) 1999;97:59-65.
Phillips MC, Olson LR. The immunologic role of the gastrointestinal tract. Crit Care Nurs Clin North Am 1993;5:107-20.
Phivthong-ngam L, Bode-Boger SM, Boger RH, Bohme M, Brandes RP, Mugge A, Frolich JC. Dietary L-arginine normalizes endothelininduced vascular contractions in cholesterol-fed rabbits. J Cardiovasc Pharmacol 1998;32:300-7.
Sato H, Zhao ZQ, McGee DS, Williams MW, Hammon JW, Jr., Vinten-Johansen J. Supplemental L-arginine during cardioplegic arrest and reperfusion avoids regional postischemic injury. J Thorac Cardiovasc Surg 1995;110:302-14.
Volta C, Bernasconi S, Iughetti L, Ghizzoni L, Rossi M, Costa M, Cozzini A. Growth hormone response to growth hormone-releasing hormone (GHRH), insulin, clonidine and arginine after GHRH pretreatment in obese children: evidence of somatostatin increase? Eur J Endocrinol 1995;132:716-21.
Wang BY, Ho HK, Lin PS, Schwarzacher SP, Pollman MJ, Gibbons GH, Tsao PS, Cooke JP. Regression of atherosclerosis: role of nitric oxide and apoptosis. Circulation 1999;99:1236-41.
Ziegler TR, Gatzen C, Wilmore DW. Strategies for attenuating proteincatabolic
responses in the critically ill. Annu Rev Med 1994;45:459-80. |
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Our Price: $11.00 |
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