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Doctors Best

High Absorption CoQ10 (100mg)
by Doctors Best
30 Softgels

CoQ10 With Bioperine For Creating High Absorption*

Our Price: $7.98
Retail Price: $11.99
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High Absorption CoQ10 contains pure, vegetarian source Coenzyme Q10 in a base of rice powder, plus Bioperine, an herbal extract that enhances CoQ10 absorption. Research studies and clinical reports suggest that CoQ10 has a broad range of applications, stemming from its ability to support the heart and cardiovascular system, the immune system, cellular energy production, liver function, nerves, and muscles.*

Boosts Cellular Energy Production
Coenzyme Q10 is a vitamin-like nutrient found in the human body. Essential to life, CoQ10 works at the cellular level to produce metabolic energy in the form of ATP. CoQ10 serves as a vital link in the electron transport chain, which is the final step in the production of ATP inside cells. Lacking adequate CoQ10, cells become energy-deficient. When cells are nourished with optimal levels of CoQ10, tissues, organs and systems perform at their peak.*

Strengthens and Protects the Heart
The heart is the hardest-working muscle in the body. Because of its high energy requirements, the heart needs to be well supplied with CoQ10 at all times. The body’s highest concentration of CoQ10 occurs in heart muscle tissue (heart muscle cells contain large numbers of mitochondria). Numerous clinical studies have demonstrated significant improvements in heart function with oral administration of CoQ10.*

Supports Immune Function
When the immune system goes into battle for us, immune cells need large amounts of energy to carry out their defensive functions. CoQ10 is required for this energy to be available. Experimental research on animals has shown that CoQ10 enhances immune functions, such as the activity of phagocytes, and antibody production. Age-related immune suppression has been observed in mice given CoQ10.*

Antioxidant Protection
CoQ10 is a versatile antioxidant which stabilizes membranes, thus protecting them from free-radical damage.* The reduced form of CoQ10, ubiquinol-10, has been found to protect LDL against peroxidation by free radicals more effectively than vitamin E, and in vitro studies suggest CoQ10 in combination with vitamin E protects LDL cholesterol from oxidation more effectively than vitamin E alone. Protecting LDL from being oxidized by free radicals is now thought to be important for cardiovascular health.*

Benefits the Gums
A number of studies have shown that CoQ10 supports repair of gingival (gum) tissue. Gingival tissues in people with periodontal disease have been found deficient in CoQ10. In several double-blind clinical trials, oral administration of CoQ10 has resulted in significant improvements.*

Bioperine — A Bioavailability-Enhancing Phytonutrient
Bioperine is a natural extract derived from black pepper that enhances nutrient absorption. Preliminary trials on humans have shown significant increases in the absorption of nutrients consumed along with Bioperine. In a recent study (publication pending), the administration of 5 mg of Bioperine together with 120 mg of CoQ10 per day resulted in a 32% increase in CoQ10 absorption after 21 days. This is especially important for individuals who have impaired absorption of fat-soluble nutrients such as CoQ10.*

Supplement Facts Serving Size: One (1) Softgel Servings Per Container: 30

	Amount Per Serving	Daily Value
Vitamin E	33 IU	110%
Coenzyme Q10 (CoQ10)	100 mg	**
Black Pepper Fruit Extract (Bioperine)	5 mg	**

The black pepper fruit extract used in this product is Bioperine, a patented standardized extract contain 95 percent piperine.

** Daily Value Not Established. Percent Daily Values are based on a 2,000 calorie diet.

Other Ingredients

Annatto Seed (for color), Gelatin, Glycerine, Lecithin, Olive Oil, Purified Water

Suggested Use

As a dietary supplement, one (1) softgel daily with food, or more as directed by your healthcare provider.

Warnings

If pregnant or nursing, consult your healthcare provider before taking this, or any, supplement. ... Keep out of reach of children. ... Store in a cool, dry place.

Allergen Info

Does NOT contain milk, egg, wheat, yeast, corn, sugar, sweeteners, starch, salt or preservatives.. Doctor's Best products are also GLUTEN FREE.

Applicable Functions

Cardiovascular Health, Cell Vitality, Cellular Oxidation, Cholesterol Health, Depleted ATP Production, Free Radicals, Gum Health, Heart Health, Heart Vitality, High Cholesterol Reduction, Hypertension Nutrition, Immune System Support, Low Energy

Related Structure Groups

Adenosine Triphosphate (ATP), Cardiovascular, Cell, Cellular Function, Gum, Heart, Immune System, Liver, Mitochondria, Muscles, Nerve, Nervous System

FAQ For CoQ10 Softgels

Q. After a month of using CoQ10 soft gels, the color of the soft gels began to slowly change. Is it still safe to take the product?
A. The gelatin used to make the soft gels is sensitive to heat and light, and exposure to these can account for changes in appearance. However, the nutrients contained in the soft gel should be unaffected, unless the exposure is extreme or prolonged.

About Doctors Best

We firmly believe that the integration of scientific research and traditional wisdom is how nutritional and herbal supplements will reach their exciting potential.

Founded in 1990 by a pioneering physician committed to science-based alternative health care, Doctor’s Best offers only the most important nutritional supplements. Careful research and precise formula development keeps us at the leading edge of quality, effectiveness, and innovation.

Containing the finest quality raw materials from around the world, Doctor’s Best supplements embody the best that traditional knowledge and current scientific research have to offer in the field of therapeutic nutrition. Countless hours have been spent analyzing scientific literature to provide sound alternatives to the proliferation of questionable supplements in the marketplace.

Each Doctor's Best product is accompanied by an annotated "Fact Sheet" with detailed background information, structure-function statements, and scientific references that substantiate these statements. All structure-function statements have been filed with the FDA in accordance with DSHEA regulations.

Traditional wisdom, up-to-date research, product quality you can trust: everything you need to develop smart strategies for achieving optimal health and well-being. We think you’ll agree that this combination of products and services is second to none.

Capsule And Tablet Information

Q. What are your capsules made of?
A. Doctor's Best capsules are typical gelatin capsules, with the exception of select products now available in veggie cap form. They are made of gelatin from cattle, like the familiar "Knox gelatin" sold in grocery stores.

The gelatin used to make Doctor's Best's capsules is manufactured in accordance with strict guidelines that ensure it is BSE-free. The FDA and the supplement industry approved these guidelines. The gelatin is made only from cattle living in non-BSE countries. All Doctor's Best capsules are in full compliance with the FDA's September 1997 industry guide, The Sourcing and Processing of Gelatin to Reduce the Potential Risk Posed by Bovine Spongiform Encephalopathy in FDA-Regulated Products for Human Use.

Q. How long does it take for a capsule to dissolve?
A. Approximately 30-45 minutes. For 2-piece gelatin capsule, the USP standard for maximum dissolution time is 45 minutes.

Q. How long does it take for a tablet to dissolve?
A. FDA Rules & Regulations require tablets to dissolve in 45 minutes or less. However, Doctor's Best sets its standards higher. They require that their tablets dissolve in 30 minutes or less. Every lot of products in tablet form is tested to verify that it dissolves in under 30 minutes.

Q. Can I find out how fast a capsule or tablet dissolves by dropping it in a glass of water or vinegar at home?
A. Testing dissolution times at home using vinegar is not an accurate way to learn what happens to capsules and tablets in your stomach. Because stomach acid is much stronger than vinegar, capsules and tablets dissolve much faster in the stomach than in a glass of water or vinegar. Also, the stomach continually "agitates" its contents, much like a washing machine does.

Vitamin And Dosage Intake

Q. Who determines what the daily dosage should be? And how is this done?
A. A panel of scientists at The Natural Academy of Sciences performs extensive research, ongoing clinical studies and scientific testing in order to determine the RDI (Recommended Daily Intake).

Q. I see that Silicon Dioxide has been used as an excipient in some of your products. Should I be concerned?
A. Silicon Dioxide is a GRAS (Generally Recognized As Safe) food additive. Numerous studies have found the following:

Q. Why is silicon dioxide used as an excipient in Doctor’s Best products? Why are excipients used at all?
A. Silicon Dioxide is used as a flow agent to enable "sticky" substances to flow through the encapsulation equipment. If silicon dioxide were not used, other flow agents would have to be used which would actually increase the number of excipients found in a given product. Ideally, the fewer excipients used, the better.

Q. Is there a limit to how many vitamins can be taken safely in one day?
A. Our bodies need vitamins and minerals, and if taken in large amounts, vitamins and minerals can adversely affect health. Large amounts of anything can be toxic. Our best advice is to work with a nutritionally aware doctor and follow label directions.

Scientific References

1. Folkers, K., Wolaniuk, A., Progress in biomedical and clinical research on coenzyme Q10. Drugs Exptl. Clin. Res. 1984; X(7):513-517.

2. Lenaz, G., et. al., “The essentially of coenzyme Q for bioenergetics and clinical medicine.” Drugs Exptl. Clin. Res. 1985; XI(8):547-556.

3. Morisco, C., Trimarco, B., Condorelli, M., “Effect of coenzyme Q10 therapy in patients with congestive heart failure: a long-term multicenter randomized study.” Clin. Investig. 1993; 71:S134-S136.

4. Mortensen, S.A., Vadhanavikit, S., Muratsu, K., Folkers, K., “Coenzyme Q10: clinical benefits with biochemical correlates suggesting a scientific breakthrough in the management of chronic heart failure.” Int. J. Tiss Reac. 1990; XII(3):155-62.

5. Poggesi, L., et. al., Effect of coenzyme Q10 on left ventricular function in patients with dilative cardiomyopathy. Current Therapeutic Research 1991; 49(5):878-886.

6. Folkers, K., Wolaniuk, A., “Research on coenzyme Q10 in clinical medicine and in immunomodulation.” Drugs Exptl. Clin. Res. 1985; XI(8):539-545.

7. Littarru, G.P., et. al., “In vitro effect of different ubiquinones on the scavenging of biologically generated O2.” Drugs Exptl. Clin. Res. 1985; XI(8):529-532.

8. Littarru, G.P. Lippa, S., “Coenzyme Q and antioxidant activity: facts and perspectives.” Drugs Exptl. Clin. Res. 1984; X(7):491-96.

9. Stocker, R., Bowry, V.W., Frei, B., “Ubiquinol-10 protects human low density lipoprotein more efficiently against lipid peroxidation than does alpha-tocopherol.” Proc. Natl. Acad. Sci. 1991; 88:1646-1650.

10. Hansen, I., Iwamoto, Y., Kishi, T., Folkers, K., “Bioenergetics in clinical medicine. IX. Gingival and leucocyte deficiencies of coenzyme Q10 in patients with periodontal disease.” Research Communications in Chemical Pathology and Pharmacology 1976; 14:729-738.

11. Wilkinson, E. Arnold, R., Folkers, K., “Treatment of Periodontal and Other Soft Tissue Diseases of the Oral Cavity with Coenzyme Q” (in) Biomedical and Clinical Aspects of Coenzyme Q 1977; 1:251-266. K. Folkers and Y. Yamaura, eds., Elsevier Science Publishing Co., N.Y.

12. Thomas, S., Neuzil, J., Stocker, R., “Cosupplementation with coenzyme Q prevents the prooxidant effect of alpha-tocopherol and increases the resistance of LDL to transition metal dependant oxidation initiation.” Arteriosclerosis, Thrombosis and Vascular Biology 1996; 16(5):687-96.

13. Badmaev, V., Majeed, M., “Comparison of Coenzyme Q10 (CoQ10) bioavailability when ingested alone and in combination with Bioperine.” Sabinsa Corporation Research Report. 1996 (unpublished).