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Glutathione Plus
by Douglas Labs
60 Capsules
Reduced L-Glutathione With N-Acetylcysteine
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Glutathione Plus capsules, provided by Douglas Laboratories, contain 50 mg of glutathione in its active reduced form, and 440 mg of N-acetyl cysteine. Glutathione is a tripeptide with antioxidant properties, and N-acetyl cysteine is a biologically
active precursor for intracellular glutathione. *
Body cells and tissues are threatened continuously by damage caused by toxic free radicals and reactive oxygen species (e.g., peroxides) which are produced
during normal oxygen metabolism, by other chemical reactions, and by toxic agents in the environment. Free radicals are capable of disrupting metabolic
activity and cell structure. When this occurs, additional free radicals are produced which, in turn, can result in more extensive damage to cells and
tissues. The uncontrolled production of free radicals is thought to be a major contributing factor to many degenerative diseases. *
Glutathione is a naturally-occurring tripeptide of Lcysteine, L-glutamate and L-glycine. Glutathione is the essential cosubstrate for two major antioxidant
enzymes in the body; glutathione peroxidase and glutathione reductase. As such, glutathione offers one mechanism for scavenging toxic free radicals.
Glutathione is well absorbed in the intestine, and enters the blood and other extracellular compartments where it exerts much of its beneficial antioxidant
effects. However, it can not effectively enter the cell. N-Acetylcysteine (NAC) is a precursor for the sulfur amino acid cysteine, and cysteine is used by the body
to synthesize glutathione. *
In contrast to glutathione, NAC is efficiently transported into the cell where it is readily converted to L-cysteine for glutathione synthesis. NAC is well absorbed, and unlike L-cysteine, is virtually nontoxic. NAC is recognized as a safe, highly effective means of increasing intracellular glutathione stores. Aside from providing cysteine as a glutathione precursor, NAC also appears to have antioxidant properties by itself, and is a valuable sulfur donor for various metabolic needs. *
Glutathione Plus combines significant levels of glutathione with N-acetylcysteine, thus providing a means of raising both extracellular and intracellular glutathione levels. *
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Supplement FactsServing Size: One (1) Capsule
Servings Per Container: 60 | | | | Amount
Per Serving | Daily
Value | Vitamin C
(As L-Ascorbic Acid) | 10 mg | 17% | Glutathione
(As L-Glutathione, Reduced) | 50 mg | ** | Cysteine
(As N-Acetyl-L-Cysteine U.S.P.) | 440 mg | ** | |
** Daily Value Not Established. Percent Daily Values are based on a 2,000 calorie diet. |
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| Also contains gelatin, silica, magenesium stearate ad water. |
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| One (1) to two (2) capsules daily at the start of a meal, or as directed by physician. It is recommended that Glutathione Plus be taken in conjunction with vitamins and minerals.Glutathione Plus capsules may be a useful nutritional adjunct for individuals who wish to increase their intake of glutathione and other cysteine-derived antioxidants. |
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| No adverse effects have been reported.Keep out of reach of children.Store in a cool, dry place, away from direct light. |
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| This product contains NO yeast, wheat, gluten, soy protein, milk/dairy, corn, sodium, sugar, starch, artificial coloring, preservatives or flavoring. |
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| Cell Formation, Cell Vitality, Free Radicals |
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| Cell, Cellular Function |
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Anonymous: Cellular antioxidant status and human immunodeficiency virus replication. Nutr Rev 1992; 50:15-18.
Aruoma OI, Halliwell B, Hoey BM, and Butler J: The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid. Free Radical Biol Med 1989; 6:593-597.
Holdiness MR: Clinical pharmacokinetics of N-acetylcysteine. Clin. Pharmacokinet. 1991; 20:123-134.
Kamei A. Glutathione levels of the human crystalline lens in aging and its antioxidant effect against the oxidation of lens proteins. Biol Pharm Bull
1993;16:870-875.
Reddy VN. Glutathione and its function in the lens--an overview. Exp Eye Res 1990;50:771-778.
Ruffman R and Wendel A: GSH rescue by N-acetylcysteine. Klin. Wochenschr. 1991; 69:857-862.
Sen CK, Atalay M, Hänninen O. Exercise-induced oxidative stress: Glutathione supplementation and deficiency. J Appl Physiol 1994;77:2177-2187.
Smilkstein MJ, Knapp GL, Kulig KW, and Rumack BH: Efficacy of oral
N-acetylcysteine in the treatment of acetaminophen overdose. N Engl J
Med 1988; 319:1557-1562. |
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Our Price: $27.40 |
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