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Garlitrin 4000

Suitable For Vegetarians
Garlitrin 4000
by PhytoPharmica
30 Enteric Coated Tablets

Closest To Fresh Garlic—without Garlic Breath!

Our Price: $8.19
Retail Price: $12.50
You Save: $4.31 each, a 34% Savings!
Add to Cart
SKU: PP18503

Garlitrin 4000, the closest to fresh garlic you’ll find, delivers 5,000 mcg of allicin, fresh garlic's most beneficial compound. However, you’ll never notice garlic breath, because the enteric-coated tablets reach the small intestine, where garlic delivers its benefits without being noticed.*

Benefits
•Clinically proven to support heart health in 15 independent studies.*
•Maintains healthy cholesterol levels that are already within the normal range.*

Key Features
•Unique, Patented Swiss Process ensures maximum absorption and freshness.*
•Contains the amount of garlic recommended by the German Commission E, the worldwide recognized authority on herbal remedies, with just 1 tablet daily!

How Does It Work?
Garlic Chemistry

Garlic contains many compounds that individually possess a wide range of beneficial effects. One of the most biologically active is allicin, which also provides garlic's distinct odor. However, allicin itself is not present in an intact garlic clove. It is formed when a clove is crushed, releasing the precursor alliin and the enzyme allinase, which then come together to form allicin, a powerful antioxidant.Several well designed, robust studies have demonstrated allicin's health supportive benefits.*

While allicin from fresh garlic has very high bioavailability, its strong odor can be problematic. Garlic odor is not merely present in breath after its consumption, it is also released through the pores of the skin, often persisting for hours or days afterwards.

The compounds in garlic have variable stability. Allinase is easily inactivated by gastric acid and allicin is fairly unstable prior to absorption in the bloodstream. Therefore, it is crucial that alliin and allinase taken in dietary supplements are introduced into the body where they can effectively create allicin.*

Garlic Supplement Disparities
Currently, there are several types of garlic supplements, including garlic oil, garlic powder, and aged garlic extract (AGE) products. Garlic oil supplements do not contain allicin, only allicin-derived compounds that have little beneficial effects at normal levels of garlic consumption. Softgel or hard shell capsulated garlic powder supplements that contain alliin and allinase are destroyed by gastric acid before they can create allicin and have minimal health supportive activity.*

Aged garlic extract products purposefully do not contain allicin. Disregarding the abundance of evidence that demonstrates the significance of allicin, the manufacturers of AGE supplements claim that other compounds are responsible for garlic's health supportive properties. Some studies have demonstrated that AGE supplements may have limited benefit. However, because AGE manufacturers sponsored these studies and their findings have yet to be replicated, leading garlic researchers question the validity of these findings. To date, the scientific consensus contends that allicin obtained from enteric-coated garlic tablets provides the most significant health supportive benefit.*



   

Supplement Facts

Serving Size: One (1) Enteric Coated Tablet
Servings Per Container: 30
 Amount
Per Serving
Daily
Value
Garlic Bulb
Extract [Standardized to Contain 3.4 Percent Alliin (11 mg)]
Allium sativum
320 mg ** 
One tablet equals 4,000 mg of fresh garlic, based on the German Commission E monograph ... Minimum of 5,000 mcg of allicin ... Minimum of 11,000 mcg of alliin ... Verified by HPLC analysis.
** Daily Value Not Established. Percent Daily Values are based on a 2,000 calorie diet.
Other Ingredients
Calcium Stearate, Cellulose, Fractionated Coconut Oil, Modified Cellulose, Modified Cellulose Gum, Silicon Dioxide, Sodium Alginate, Stearic Acid, Titanium Dioxide, Vegetable Glycerin
Suggested Use
As a dietary supplement, one (1) tablet daily with food, or more as directed by your healthcare provider. ... DO NOT CHEW OR CRUSH.
Warnings
If pregnant, nursing, or taking prescription drugs, consult your healthcare practitioner prior to use. ... Keep out of reach of children. ... Store in a cool, dry place.
Allergen Info
This product contains NO sugar, salt, yeast, wheat, gluten, corn, soy, dairy products, artificial flavoring, preservatives or ingredients of animal origin. All colors used are from natural sources.



Applicable Functions
Cardiac Health, Cardiovascular Health, Cell Vitality, Cellular Oxidation, Free Radicals, Heart Health, Heart Vitality, Immune System Support, Lipid Peroxidation
Related Structure Groups
Cardiac, Cardiovascular, Cell, Cellular Function, Heart, Immune System
About PhytoPharmica

Nature Makes It Pure. Science Makes It Work.

Our People
PhytoPharmica, a division of Enzymatic Therapy Inc., sparks with the enthusiasm that comes from knowing that you're helping create the best supplements in the nation. Our team is made of people who are natural explorers--passionate about the healthful ingredients found in nature--but committed to finding the most pure and effective combinations backed by rigorous research. This buzz doesn't just end at the lab door. Everyone here--from our staff of scientists to our crews running the pharmaceutical-grade machinery, to our customer service professionals share the exuberance of helping improve the health of America, one customer at a time.

Our Reputation
PhytoPharmica provides the finest therapeutic-dosage, natural medicines and nutritional supplements in the nation. We strive to bring the best for your health.

Our Difference
One thing that sets us apart from the others is the way we make our products. Everything from raw material evaluation, supplier selection, laboratory analysis and manufacturing standards to conform to the FDA's verified good manufacturing practices--known in the industry as "GMPs."

FAQ
What’s the difference between aged versus fresh garlic?
Aged and fresh garlic extracts are processed very differently and contain different components. To make aged garlic, garlic is placed in an ethanol solution and stored for 20 months. Aged garlic extract contains S-allyl mercaptocysteine (SAMC), a compound that AGE makers claim is the reason garlic is so good for us. Interestingly, fresh garlic does not contain any SAMC. It only appears after the aging process. Although a body of research has been developed for aged garlic, there have been no successful independent replications of aged garlic studies.

Allicin is the key proven compound found in fresh, not aged, garlic. Allicin is a complex compound that is only released when a garlic clove is crushed (that’s what you smell when you mince garlic). Allicin acts as an antioxidant, helps support cardiovascular health, and supports the immune system.* Aged garlic yields no beneficial allicin.

Is Garlitrin 4000 enteric coated? Why does it matter?
Yes, Garlitrin 4000 is enteric coated. An enteric-coated product utilizes a protective outer layer to keep the beneficial garlic extract contained until it reaches the alkaline environment of the small intestine. There, the tablet dissolves, slowly releasing alliin and allinase to form allicin, which is absorbed into the bloodstream as it travels slowly through the small intestine.*

Garlitrin 4000 also uses the combination of a special formulation and the enteric coating to keep the key components of garlic’s active ingredient, allicin, separate until they are released and combined in the small intestine. This ensures optimal absorption and reduces the odor often associated with garlic.
References
1. Blumenthal M, ed. Garlic (Allii sativi bulbous). In: The Complete German Commission E Monographs. Therapeutic Guide to Herbal Medicines. Austin, Tex: American Botanical Council; 1998: 134-135.

2. Fleming T., ed. Garlic (Allium sativum). In: PDR for Herbal Medicines. Montvale, NJ: Medical Economics Company; 2000: 327-331.

3. Koch HP. Therapeutic Effects and Applications of Garlic and its Preparations. In: Garlic: The Science and Therapeutic Application of Allium sativum L. and Related Species. Koch HP, Lawson L. eds. Baltimore, Md: Williams and Wilkins; 1996:38,103,153-162.

4. Lawson L, Wang J. The common metabolism of allicin and allicin-derived compounds in humans and allicin release from garlic compounds. Presentation at the American Herbal products Association International Garlic Symposium. August 1st, 2001.

5. Krest I, Keusgen M. Stabilization and pharmaceutical use of alliinase. Pharmazie. 1999;54:289-93.

6. Zhang XH, Lowe D, Giles P, Fell S, Connock MJ, Maslin DJ. Gender may influence the action of garlic oil on plasma cholesterol and glucose levels of normal subjects. J Nutr.2001;131:1471-1478.

7. Berthold HK, Sudhop T, von Bergmann K. Effect of a garlic oil preparation on serum lipoproteins and cholesterol metabolism: a randomized controlled trial. JAMA. 1998;17:1900-1902.

8. Staba EJ, Lash L, Staba JE. A commentary on the effects of garlic extraction and formulation on product composition. J Nutr. 2001;131:1118S-1119S.

9. Isaacsohn JL, Moser M, Stein EA, et al. Garlic powder and plasma lipids and lipoproteins: a multicenter, randomized, placebo-controlled trial. Arch Intern Med. 1998;158:1189-1194.

10. Spigelski D, Jones PJ. Efficacy of garlic supplementation in lowering serum cholesterol levels. Nutr Rev. 2001;59:236-241.

11. Amagase H, Petesch BL, Matsuura H, Kasuga S, Itakura Y. Intake of garlic and its bioactive components. J Nutr. 2001;131:955S-62S.

12. Amagase H, Block E, Bordia A, Lawson LD. The controversial issues surrounding allicin versus non-allicin containing products. Panel Discussion. Presentation at the American Herbal products Association International Garlic Symposium. August 1st, 2001.

13. Rabinkov A, Miron T, Konstantinovski L, Wilchek M, Mirelman D, Weiner L. The mode of action of allicin: trapping of radicals and interaction with thiol containing proteins. Biochim Biophys Acta. 1998;1379:233-44.

14. Das I, Khan NS, Sooranna SR. Nitric oxide synthase activation is a unique mechanism of garlic action. Biochem Soc Trans. 1995;23:136S.

15. Kim-Park S, Ku DD. Garlic elicits a nitric oxide-dependent relaxation and inhibits hypoxic pulmonary vasoconstriction in rats. Clin Exp Pharmacol Physiol. 2000;27:780-6.

16. Kannar D, Wattanapenpaiboon N, Savige GS, Wahlqvist ML. Hypocholesterolemic effects of an enteric-coated garlic supplement. J Am Coll Nutr. 2001;20:225-31.

17. Koscielny J, Klussendorf D, Latza R, Schmitt R, Radtke H, Siegel G, et al. The antiatherosclerotic effect of Allium sativum. Atherosclerosis. 1999;144:237-259.

18. Orekhov AN, Grunwald J. Effects of garlic on atherosclerosis. Nutrition. 1997;13:656-663.

19. Josling P. Preventing the common cold with a garlic supplement: a double blind, placebo-controlled survey. Adv Ther. 2001;18:189-93.

20. Milner JA. A historical perspective on garlic and cancer. J Nutr. 2001;131:1027-31.

21. Salman H, Bergman M, Bessler H, Punsky I, Djaldetti M. Effect of a garlic derivative (alliin) on peripheral blood cell immune responses. Int J Immunopharmacol. 1999;21:589-97.

22. Tang Z, Sheng Z, Liu S, Jian X, Sun K, Yan M. The preventing function of garlic on experimental oral precancer and its effect on natural killer cells, T-lymphocytes and interleukin-2. Hunan I Ko Ta Hsueh Hsueh Pao. 1997;22:246-248.

23. Ankri S, Miron T, Rabinkov A, Wilchek M, Mirelman D. Allicin from garlic strongly inhibits cysteine proteinases and cytopathic effects of Entamoeba histolytica. Antimicrob Agents Chemother. 1997;41:2286-8.

24. Jonkers D, van den Broek E, van Dooren, et al. Antibacterial effect of garlic and omeprazole on Helicobacter pylori. J Antimicrob Chemother. 1999;43:837-9.

25. Kockar C, Ozturk M, Bavbek N. Helicobacter pylori eradication with beta-carotene, ascorbic acid and allicin. Acta Medica (Hradec Kralove). 2001;44:97-100.

26. Klemen H. Enzymatic Therapy Director of Quality Control Laboratory. In-house communication (electronic mail). November 5, 2002.
Garlitrin 4000 Our Price: $8.19
Retail Price: $12.50
You Save: $4.31 each, a 34% Savings!
Add to Cart
SKU: PP18503
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