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DIM Enhanced Delivery System by Allergy Research Group 120 Vegetarian Capsules
BioResponse DIM™ with Vitamin E Succcinate
Our Price: $26.40 Retail Price: $44.00 You Save: $17.60 each, a 40% Savings! | 
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DIM Enhance Delivery System contains BioResponse DIM, a unique formulation containing pure diindolylmethane, an indole. Indoles are plant compounds with health promoting properties, found in cruciferous vegetables such as broccoli, cabbage, cauliflower and Brussels sprouts. Patented BioResponse DIM is ten times more potent than indole-3-carbinole (I3C).* I3C is highly unstable and has no biologic activity until it is converted to DIM. Conversion of I3C takes place in the stomach and requires an appropriately acidic environment. In contrast to I3C, DIM is highly stable, requires no conversion in the stomach, and is the most active cruciferous phytonutrient in promoting beneficial estrogen metabolism.* DIM is often preferred by clinicians over I3C. Diindolylmethane, or DIM has been shown to help regulate and promote a more efficient metabolism of estrogen, by supporting the body in metabolizing estrogen into more of the protective 2-hydroxyesterone rather than the proliferative 16-hydroxyesterone.* IndoleGard is a stable bioavailable form of DIM, made possible through a proprietary delivery system. The formula is co-solubilized with phosphatidylcholine, and microencapsulated in starch particles.
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Supplement Facts
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| Four Vegetarian Capsules Contain: |
Amount Per Serving |
BioResponse DIM™ A patented Diindolylmethane complex, containing starch, DIM (25% min.), Vitamin E succinate, phosphatidylcholine (from soy), silica | 300 mg |
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| L-Leucine, Hydroxypropyl Methylcellulose, Cellulose |
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| As a dietary supplement, two to four (2 - 4) capsules one or two (1 - 2) times daily , or as directed by a healthcare practitioner. |
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| Do not use this product if you are pregnant or lactating, or using birth control pills. Harmless changes in urine color may occur. Increased water consumption reverses this side effect.* Contains ingredient(s) derived from SOY. |
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| Estrogen Support, Hormone |
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| Hormonal Imbalances, Mood Swings, Overweight |
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| Abdomen, Pituitary, Thyroid |
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| Abrasiveness, Displeased, Uncomfortable |
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DIM® (Diindolylmethane) has been shown to help regulate and promote a more efficient metabolism of estrogen, and an optimal ratio of estrogen metabolites.* DIM® Enhanced Delivery System from Allergy Research Group® contains BioResponse DIM™, a unique formulation containing pure Diindolylmethane, an indole. Indoles are plant compounds with health promoting properties, and are found in cruciferous vegetables such as broccoli, cabbage, cauliflower and Brussels sprouts.DIM® Enhanced Delivery System is a stable, bioavailable form of DIM®, made possible through a proprietary delivery system. The formula is co-solubilized with phosphatidylcholine, and microencapsulated in starch particles. Research over the past thirty years has determined that disrupted estrogen metabolism is closely linked to several health risks in men and women, particularly those involving the breast, uterus, prostate and other reproductive tissue. Genetics, excess weight, poor diet and other lifestyle factors may result in an imbalance of estrogen metabolites. Xenoestrogenic compounds of the modern world, such as organochlorine pesticides, can significantly disrupt healthy estrogen metabolism.* These estrogen disruptors alter estradiol hydroxylation metabolism producing a higher ratio of the genotoxic 16 alpha-hydroxyestrone (16 a-OHE1) to the safer and weaker estrogenic 2-hydroxyestrone (2-OHE1). The genotoxic 16 a-OHE1 stimulates cellular proliferation, increases oncogene expression, and inhibits apoptosis. It is clear that modulating these aspects of estrogen metabolism, particularly the production of 16 a-OHE1, can contribute to healthy aging.* The phytochemicals in cruciferous vegetables have been shown to beneficially affect the body's hormonal and detoxification systems. Epidemiological studies have supported the health benefits of consuming these vegetables.* DIM® is a major active acid-catalyzed derivative of one of the phytochemicals in cruciferous vegetables, indole-3-carbinol (I3C). DIM® is thought to be responsible for the health effects of dietary I3C. Research using human breast cells (MCF-7) has shown that DIM® not only inhibits cell growth, but also induces apoptosis. These results involve DIM® binding to the aryl hydrocarbon receptor (AhR) resulting in rapid formation of the nuclear AhR complex and consequent induction of gene expression and synthesis of cytochrome P450 detoxification enzyme (CyP450A1). DIM® consequently produces increased levels of the protective hydroxylated estrogen 2-OHE1.* The mechanisms for DIM's health benefits primarily involve the induction of mixed function oxidases and phase II detoxification enzyme systems by the binding and activation of the arylhydrocarbon receptor. Some have suggested that DIM® may also positively affect cellular signaling pathways, and thus regulate tumor promotion and progression. It is becoming increasingly apparent that dietary supplements like DIM® may provide an important mechanism for maintaining successful aging despite the increasing levels of xenoestrogenic compounds in our modern world.* |
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| Detailed Technical Information |
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Our Price: $26.40 Retail Price: $44.00 You Save: $17.60 each, a 40% Savings! |

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